We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Case report: Mononeuropathy multiplex of extranodal natural killer/T-cell lymphoma misdiagnosed as systemic vasculitis.
- Authors
Jiayu Shi; Jingwen Niu; Di Wu; Lei Zhang; Yangyu Huang; Hui Zhang; Hongzhi Guan; Mingsheng Liu; Yuzhou Guan
- Abstract
Background: Extranodal NK/T-cell lymphoma (ENKTL) is an aggressive non-Hodgkin lymphoma that typically develops in the upper aerodigestive tract. Case presentation: We encountered an ENKTL patient who presented with purpura-like rashes and foot drops as initial symptoms and later developed other peripheral nerve involvement. The nerve conduction study of both the motor nerve and the sensory nerve showed axonal damage resembling mononeuropathy multiplex. Although the initial response to steroids was encouraging, the patient's symptoms reappeared and aggravated. A biopsy of the abdominal subcutaneous fat tissue with additional immunohistochemistry revealed neoplastic NK/T lymphocytes. Conclusion: We reported the first case presented as mononeuropathy multiplex as the initial clinical manifestation in ENKTL patients. Lymphoma should be considered in the diagnosis of atypical mononeuropathy in multiplex patients.
- Subjects
NERVE conduction studies; LYMPHOMAS; NON-Hodgkin's lymphoma; ADIPOSE tissues; PERIPHERAL nerve tumors; MUCOCUTANEOUS lymph node syndrome
- Publication
Frontiers in Neurology, 2023, p1
- ISSN
1664-2295
- Publication type
Article
- DOI
10.3389/fneur.2023.1283874