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- Title
Effectiveness of Pisang Raja Peel Extract (Musa Paradisiaca L) on Bacterial Growth of Porphyromonas Gingivalis as the Cause of Periodontitis.
- Authors
Eva, Andy Fairuz Zuraida; Masriadi; Hasanuddin, Nur Rahmah; Mallombasang, Andi Tenri Biba; Ajis, Muhammad
- Abstract
Background. Periodontal disease is a chronic inflammatory infection that causes damage to the tissue supporting the teeth. The most common periodontal diseases are gingivitis and periodontitis. Periodontitis is a complex, localized chronic inflammatory disease characterized by the destruction of connective tissue, periodontal ligaments, and bone supporting teeth. This periodontal disease is caused by plaque bacteria on the surface of the teeth, where the plaque is a thin layer of biofilm containing a collection of pathogenic microorganisms such as Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans, Prevotella intermedia, Tannerella forsythia and Fusobacterium nucleatum which are soft deposits. Porphyromonas gingivalis is a gram-negative, black pigmented, rod-shaped anaerobic bacteria. Porphyromonas gingivalis is one of the dominant bacteria in chronic periodontitis which is found in subgingival plaques. Indonesia is a country with a tropical climate which makes it rich in biodiversity, which can be used as antibacterial agents. Plantain (Musa Paradisiaca L) is a fruit that is easy to get, but the skin is rarely used. The Pisang Raja peel (Musa Paradisaca L) contains chemical compounds saponins, tannins, flavonoids, and alkaloids which have antimicrobial properties. Objective: To determine the effectiveness of Pisang Raja peel (Musa Paradisiaca L) extract against the inhibition of Porphyromonas gingivalis bacteria as a cause of periodontitis. Methods: Using laboratory experimental methods, the test was carried out in the laboratory with the form of research in the form of Posttest Only Control Design and sampling by random sampling through 4 treatments and 6 repetitions. Statistical test was One Way Anova. Results: Based on the oneway Anova test, the concentration group of 16%, 32%, and 64% and the control group obtained a p-value of (p <0.01) which means that there is a significant difference. Conclusion: Based on the results of this study, it is shown that the effectiveness of Pisang Raja peel extracts concentrations with concentration 16%, 32%, and 64% in inhibiting Porphyromonas gingivalis bacteria and control group obtained p-value (p<0,01) means there was significant correlation. Conclusion: Based on this research that there is effective correlation Pisang Raja peel extract with concentration 16%, 32%, dan 64% can inhibit the growth Porphyromonas gingivalis.
- Subjects
INDONESIA; PLANTAIN banana; PORPHYROMONAS gingivalis; ACTINOBACILLUS actinomycetemcomitans; BACTERIAL growth; PERIODONTITIS; FLAVONOIDS; PHYTOCHEMICALS; ALVEOLAR process
- Publication
Indian Journal of Forensic Medicine & Toxicology, 2022, Vol 16, Issue 1, p237
- ISSN
0973-9122
- Publication type
Article
- DOI
10.37506/ijfmt.v16i1.17459