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- Title
Quinine May Trigger Torsades de Pointes During Astemizole Therapy.
- Authors
Martin, Emory S.; Rogalski, Kathy; Black, James N.
- Abstract
Because of serious cardiovascular events, warnings against concomitant use of certain medications with the use of antihistamine (HismanalR have been published and added to product labeling. Quinine, the optical isomer to quinidine, is included in these warnings. We present the case of a patient with only mild electrolyte disturbances who experienced an episode of torsades de pointes after a single dose of quinine while taking astemizole.
- Subjects
ASTEMIZOLE; ANTIHISTAMINES; QUININE; PRODUCT management; QUINIDINE; CARDIOVASCULAR agents
- Publication
Pacing & Clinical Electrophysiology, 1997, Vol 20, Issue 8, p2024
- ISSN
0147-8389
- Publication type
Article
- DOI
10.1111/j.1540-8159.1997.tb03613.x