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- Title
Aortic annular plane systolic excursion in cats with hypertrophic cardiomyopathy.
- Authors
Dutton, Luke C.; Spalla, Ilaria; Seo, Joonbum; Silva, Joel; Novo Matos, Jose
- Abstract
Background: Impairment of left ventricular (LV) longitudinal function is an early marker of systolic dysfunction in hypertrophic cardiomyopathy (HCM). Aortic annular plane systolic excursion (AAPSE) is a measure of LV longitudinal function in people that has not been evaluated in cats. Hypothesis: Aortic annular plane systolic excursion is lower in cats with HCM compared to control cats, and cats in stage C have the lowest AAPSE. Animals: One hundred seventy‐five cats: 60 normal, 61 HCM stage B and 54 HCM stage C cats. Materials: Multicenter retrospective case‐control study. Electronic medical records from 4 referral hospitals were reviewed for cats diagnosed with HCM and normal cats. HCM was defined as LV wall thickness ≥6 mm and normal cats ≤5 mm. M‐mode bisecting the aorta in right parasternal short‐axis view was used to measure AAPSE. Results: Aortic annular plane systolic excursion was lower in HCM cats compared to normal cats (3.9 ± 0.9 mm versus 4.6 ± 0.9 mm, P <.001) and was lowest in HCM stage C (2.4 ± 0.6 mm, P <.001). An AAPSE <2.9 mm gave a sensitivity of 83% (95% CI 71%‐91%) and specificity of 92% (95% CI 82%‐97%) to differentiate HCM stage C from stage B. AAPSE correlated with mitral annular plane systolic excursion (r =.6 [.4‐.7], P <.001), and atrial fractional shortening (r =.6 [.5‐.7], P <.001), but showed no correlation with LV fractional shortening. Conclusions and Clinical Importance: Aortic annular plane systolic excursion is an easily acquired echocardiographic variable and might be a new measurement of LV systolic performance in cats with HCM.
- Subjects
HYPERTROPHIC cardiomyopathy; CATS; AORTA; CAT diseases; ELECTRONIC health records
- Publication
Journal of Veterinary Internal Medicine, 2024, Vol 38, Issue 1, p61
- ISSN
0891-6640
- Publication type
Article
- DOI
10.1111/jvim.16962