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- Title
Augmented Fragmentation of Atrial Activity Upon Premature Electrical Stimuli by Verapamil.
- Authors
Aizawa, Y.; Miyajima, S.; Niwano, S.; Tamura, M.; Shibata, A.
- Abstract
The significance of fragmented activity obtained from the atrium during electrophysiologic study (EP study) was confirmed since it was always observed just at the onset of fibrillation. It was preceded by extra stimuli or atrial flutter, and the initial site of fragmentation varied from case to case. The premature-stimu- luse-induced widening of the atrial wave was observed in some cases who had normal size of atrium and no heart failure. The widening was augemented by administration of verapamil but not by procainamide, suggesting that for such widening or fragmented activity, slow-fiber-mediated conduction seems to be responsible. One case with intraatrial reentrant tachycardia developed fragmentation lasting for 1.0 second after verapamil. Therefore, some apparently normal atria may have a subclinical electro physiologic abnormality that can be disclosed by premature stimulations or verapamil.
- Subjects
HEART diseases; ELECTROPHYSIOLOGY; NEUROLOGY; VENTRICULAR fibrillation; CARDIAC arrest; CARDIOVASCULAR diseases
- Publication
Angiology, 1989, Vol 40, Issue 2, p94
- ISSN
0003-3197
- Publication type
Article
- DOI
10.1177/000331978904000203