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Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30968-3
By:
- Lim, Elaine T.;
- Chan, Yingleong;
- Dawes, Pepper;
- Guo, Xiaoge;
- Erdin, Serkan;
- Tai, Derek J. C.;
- Liu, Songlei;
- Reichert, Julia M.;
- Burns, Mannix J.;
- Chan, Ying Kai;
- Chiang, Jessica J.;
- Meyer, Katharina;
- Zhang, Xiaochang;
- Walsh, Christopher A.;
- Yankner, Bruce A.;
- Raychaudhuri, Soumya;
- Hirschhorn, Joel N.;
- Gusella, James F.;
- Talkowski, Michael E.;
- Church, George M.
Publication type:
Article
16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23113-z
By:
- Sundberg, Maria;
- Pinson, Hannah;
- Smith, Richard S.;
- Winden, Kellen D.;
- Venugopal, Pooja;
- Tai, Derek J. C.;
- Gusella, James F.;
- Talkowski, Michael E.;
- Walsh, Christopher A.;
- Tegmark, Max;
- Sahin, Mustafa
Publication type:
Article
Biallelic mutation of FBXL7 suggests a novel form of Hennekam syndrome.
Published in:
American Journal of Medical Genetics. Part A, 2020, v. 182, n. 1, p. 189, doi. 10.1002/ajmg.a.61392
By:
- Boone, Philip M.;
- Paterson, Scott;
- Mohajeri, Kiana;
- Zhu, Wenmiao;
- Genetti, Casie A.;
- Tai, Derek J. C.;
- Nori, Neeharika;
- Agrawal, Pankaj B.;
- Bacino, Carlos A.;
- Bi, Weimin;
- Talkowski, Michael E.;
- Hogan, Benjamin M.;
- Rodan, Lance H.
Publication type:
Article
Novel role and mechanism of protein inhibitor of activated STAT1 in spatial learning.
Published in:
EMBO Journal, 2011, v. 30, n. 1, p. 205, doi. 10.1038/emboj.2010.290
By:
- Tai, Derek J C;
- Hsu, Wei L;
- Liu, Yen C;
- Ma, Yun L;
- Lee, Eminy H Y
Publication type:
Article
Restoring Wnt6 signaling ameliorates behavioral deficits in MeCP2 T158A mouse model of Rett syndrome.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-57745-w
By:
- Hsu, Wei-Lun;
- Ma, Yun-Li;
- Liu, Yen-Chen;
- Tai, Derek J. C.;
- Lee, Eminy H. Y.
Publication type:
Article
MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome.
Published in:
Nature Communications, 2016, v. 7, n. 2, p. 10552, doi. 10.1038/ncomms10552
By:
- Tai, Derek J. C.;
- Liu, Yen C.;
- Hsu, Wei L.;
- Ma, Yun L.;
- Cheng, Sin J.;
- Liu, Shau Y.;
- Lee, Eminy H. Y.
Publication type:
Article
Aβ activation of SGK1 and increase in Mcl-1 expression protects against Aβ-induced toxicity in PC12 cells.
Published in:
FASEB Journal, 2008, v. 22, p. 290, doi. 10.1096/fasebj.22.2_supplement.290
By:
- Lee, Eminy H.Y.;
- Hsu, Wei L.;
- Wang, Ling D.;
- Chiu, Tsai C.;
- Tai, Derek J. C.
Publication type:
Article
Transcriptional consequences of MBD5 disruption in mouse brain and CRISPR-derived neurons.
Published in:
Molecular Autism, 2020, v. 11, n. 1, p. 1, doi. 10.1186/s13229-020-00354-1
By:
- Seabra, Catarina M.;
- Aneichyk, Tatsiana;
- Erdin, Serkan;
- Tai, Derek J. C.;
- De Esch, Celine E. F.;
- Razaz, Parisa;
- An, Yu;
- Manavalan, Poornima;
- Ragavendran, Ashok;
- Stortchevoi, Alexei;
- Abad, Clemer;
- Young, Juan I.;
- Maciel, Patricia;
- Talkowski, Michael E.;
- Gusella, James F.
Publication type:
Article
CREB SUMOylation by the E3 Ligase PIAS1 Enhances Spatial Memory.
Published in:
Journal of Neuroscience, 2014, v. 34, n. 29, p. 9574, doi. 10.1523/JNEUROSCI.4302-13.2014
By:
- Yan-Chu Chen;
- Wei-Lun Hsu;
- Yun-Li Ma;
- Tai, Derek J. C.;
- Lee, Eminy H. Y.
Publication type:
Article

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