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- Title
Carlos Gutiérrez-Merino: Synergy of Theory and Experimentation in Biological Membrane Research.
- Authors
Antollini, Silvia S.; Barrantes, Francisco J.
- Abstract
Professor Carlos Gutiérrez-Merino, a prominent scientist working in the complex realm of biological membranes, has made significant theoretical and experimental contributions to the field. Contemporaneous with the development of the fluid-mosaic model of Singer and Nicolson, the Förster resonance energy transfer (FRET) approach has become an invaluable tool for studying molecular interactions in membranes, providing structural insights on a scale of 1–10 nm and remaining important alongside evolving perspectives on membrane structures. In the last few decades, Gutiérrez-Merino's work has covered multiple facets in the field of FRET, with his contributions producing significant advances in quantitative membrane biology. His more recent experimental work expanded the ground concepts of FRET to high-resolution cell imaging. Commencing in the late 1980s, a series of collaborations between Gutiérrez-Merino and the authors involved research visits and joint investigations focused on the nicotinic acetylcholine receptor and its relation to membrane lipids, fostering a lasting friendship.
- Subjects
BIOLOGICAL membranes; FLUORESCENCE resonance energy transfer; NICOTINIC acetylcholine receptors; MEMBRANE lipids; CELL imaging; NICOTINIC receptors
- Publication
Molecules, 2024, Vol 29, Issue 4, p820
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules29040820