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- Title
Clinical Effect of Moisturized Skin Care on Radiation Dermatitis of Head and Neck Cancer.
- Authors
PEI-CHUAN TSAI; YU-CHANG LIU; TZONG SHIUN LI; FEI-TING HSU; YUAN-HAO LEE; I-TSANG CHIANG; YUAN CHANG; CHIU-HSIANG LEE
- Abstract
Background/Aim: Radiation therapy (RT) for head and neck cancer may cause severe radiation dermatitis (RD) resulting in RT interruption and affecting disease control. A few studies address skin moisture changes during RT for head and neck cancer. The purpose of this study was to explore the effect of moisturized skin care (MSC) on severity of RD. Patients and Methods: The study includes newly diagnosed head and neck cancer patients undergoing RT. Participants were divided into MSC group and routine skin care (RSC) group based on patient's preferred decision. Skin moisture in the four quadrants of the neck was measured weekly before and after RT. RD was assessed with the Radiation Induced Skin Reaction Assessment Scale (RISRAS) and the Radiation Therapy Oncology Group (RTOG) acute skin toxicity grading criteria. Results: A total of 54 patients were enrolled, of which 49 patients were suitable for the statistical analysis. There was a statistically significant difference in the RISRAS total score since the 5th week after RT between the groups. The severity of RD was less (B=0.814, p=0.021) and the onset was later (B=-0.384, p=0.006) in the MSC group when compared to the RSC group. Skin moisture decreased with cumulative radiation dose. In the upper neck, the MSC group had a slower rate of skin moisture decrease compared to the RSC group (right upper neck: B=0.935, p=0.007; left upper neck: B=0.93, p=0.018). Conclusion: MSC can effectively reduce the severity and delay the onset of RD, while slows down skin moisture decrease during RT.
- Subjects
SKIN inflammation; HEAD &; neck cancer treatment; CANCER radiotherapy; SKIN care; MEDICAL decision making
- Publication
In Vivo, 2023, Vol 37, Issue 6, p2776
- ISSN
0258-851X
- Publication type
Article
- DOI
10.21873/invivo.13389