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- Title
АЛКОХОЛНА ИНТОКСИКАЦИЯ И ЕНЗИМНИ АНТИОКСИДАНТИ.
- Authors
Туфкова, С.; Паскалева, Д.; Сандева, М.
- Abstract
The enzymatic antioxidants play a major role in the formation of internal tolerance of antioxidant capacity. They neutralize and eliminate directly the toxic reactive metabolites of oxygen. Aim: Study of enzymatic antioxidants – SOD and GPx, in patients with acute alcohol intoxication. Material and Methods: The study is prospective longitudinal of 33 patients, with moderate and severe acute alcohol poisoning (n = 33) and a control group (n = 35). Clinical-laboratory tests have been performed according to the certain standards of clinical laboratory. Results: Data was established on statistically significant decrease of the enzymatic antioxidant activity of SOD (р < 0,001) and GPx (p < 0,05) in acute alcohol intoxication, without them correlating with the severity of the intoxication. Conclusion: A reliable marker for the complex evaluation of the antioxidant system in humans, is the tracking of a “specific set” of antioxidant indicators and their careful interpretation.
- Publication
General Medicine / Obsta Medicina, 2019, Vol 21, Issue 6, p14
- ISSN
1311-1817
- Publication type
Article