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- Title
The Assessment of COVID-19 Pneumonia in Neonates: Observed by Lung Ultrasound Technique and Correlated with Biomarkers and Symptoms.
- Authors
Stoicescu, Emil Robert; Manolescu, Diana Luminita; Iacob, Roxana; Cerbu, Simona; Dima, Mirabela; Iacob, Emil Radu; Ciuca, Ioana Mihaiela; Oancea, Cristian; Iacob, Daniela
- Abstract
Newborns infected with SARS-CoV2 infection develop different symptoms in comparison with adults, but one thing is clear: some of the most common manifestations include cough and other respiratory symptoms that need to be evaluated. In these cases, lung ultrasound is a useful imaging technique that can evaluate the newborns' lung damage caused by COVID-19 pneumonia and can be used for the surveillance of the patients as well, being non-irradiating and easy to use. Nineteen neonates who were confirmed as having SARS-CoV2 infection were investigated using this imaging tool, and the results were compared and correlated with their symptoms and biomarkers. The mean of LUSS was 12.21 ± 3.56 (S.D), while the 95% CI for the arithmetic mean was 10.49–13.93. The difference of an independent t-test between the LUSS for the patient who presented cough and the LUSS for the patient without cough was −4.48 with an associated p-value of p = 0.02. The Pearson's correlation coefficient r = 0.89 (p = 0.03, 95% CI 0.0642 to 0.993) between the LUSS and IL-6 level showed a positive strong correlation. This reliable correlation between lung ultrasound score and inflammatory markers suggests that LUS could be used for monitoring inflammatory lung diseases in the future.
- Subjects
COUGH; NEWBORN infants; COVID-19; ULTRASONIC imaging; SYMPTOMS; MULTISYSTEM inflammatory syndrome
- Publication
Journal of Clinical Medicine, 2022, Vol 11, Issue 12, p3555
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm11123555