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Beta-Amyloid and Its Asp7 Isoform: Morphological and Aggregation Properties and Effects of Intracerebroventricular Administration.
Published in:
Brain Sciences (2076-3425), 2024, v. 14, n. 10, p. 1042, doi. 10.3390/brainsci14101042
By:
- Ushakova, Valeriya;
- Zorkina, Yana;
- Abramova, Olga;
- Kuanaeva, Regina;
- Barykin, Evgeny;
- Vaneev, Alexander;
- Timoshenko, Roman;
- Gorelkin, Peter;
- Erofeev, Alexander;
- Zubkov, Eugene;
- Valikhov, Marat;
- Gurina, Olga;
- Mitkevich, Vladimir;
- Chekhonin, Vladimir;
- Morozova, Anna
Publication type:
Article
Isomerization and phosphorylation significantly influence the effect of beta amyloid on blood‐brain barrier endothelial cells.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072971
By:
- Petrovskaya, Aleksandra;
- Tverskoi, Artem;
- Barykin, Evgeny;
- Varshavskaya, Kseniya;
- Dalina, Alexandra;
- Mitkevich, Vladimir;
- Makarov, Alexander;
- Petrushanko, Irina
Publication type:
Article
Identification of α4β2 nAChR interaction site with Aβ<sub>42</sub> and development of tetrapeptide capable of breaking this interaction: Molecular and cell biology/receptors.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040936
By:
- Barykin, Evgeny;
- Garifulina, Alexandra;
- Adzhubei, Alexei;
- Shelukhina, Irina;
- Kozin, Sergey A.;
- Mitkevich, Vladimir;
- Tsetlin, Victor;
- Makarov, Alexander
Publication type:
Article
Distinct Effects of Beta-Amyloid, Its Isomerized and Phosphorylated Forms on the Redox Status and Mitochondrial Functioning of the Blood–Brain Barrier Endothelium.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 183, doi. 10.3390/ijms24010183
By:
- Petrovskaya, Aleksandra V.;
- Tverskoi, Artem M.;
- Barykin, Evgeny P.;
- Varshavskaya, Kseniya B.;
- Dalina, Alexandra A.;
- Mitkevich, Vladimir A.;
- Makarov, Alexander A.;
- Petrushanko, Irina Yu.
Publication type:
Article
Synthetic, Cell-Derived, Brain-Derived, and Recombinant β-Amyloid: Modelling Alzheimer's Disease for Research and Drug Development.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 15036, doi. 10.3390/ijms232315036
By:
- Varshavskaya, Kseniya B.;
- Mitkevich, Vladimir A.;
- Makarov, Alexander A.;
- Barykin, Evgeny P.
Publication type:
Article
The Dynamics of β-Amyloid Proteoforms Accumulation in the Brain of a 5xFAD Mouse Model of Alzheimer's Disease.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 27, doi. 10.3390/ijms23010027
By:
- Bugrova, Anna E.;
- Strelnikova, Polina A.;
- Indeykina, Maria I.;
- Kononikhin, Alexey S.;
- Zakharova, Natalia V.;
- Brzhozovskiy, Alexander G.;
- Barykin, Evgeny P.;
- Pekov, Stanislav I.;
- Gavrish, Maria S.;
- Babaev, Alexey A.;
- Kosyreva, Anna M.;
- Morozova, Anna Y.;
- Degterev, Daniil A.;
- Mitkevich, Vladimir A.;
- Popov, Igor A.;
- Makarov, Alexander A.;
- Nikolaev, Evgeny N.
Publication type:
Article
Tetrapeptide Ac-HAEE-NH2 Protects α4β2 nAChR from Inhibition by Aβ.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 6272, doi. 10.3390/ijms21176272
By:
- Barykin, Evgeny P.;
- Garifulina, Aleksandra I.;
- Tolstova, Anna P.;
- Anashkina, Anastasia A.;
- Adzhubei, Alexei A.;
- Mezentsev, Yuri V.;
- Shelukhina, Irina V.;
- Kozin, Sergey A.;
- Tsetlin, Victor I.;
- Makarov, Alexander A.
Publication type:
Article
Cell stiffness and ROS level alterations in living neurons mediated by β-amyloid oligomers measured by scanning ion-conductance microscopy.
Published in:
2021
By:
- Suchalko, Oleg;
- Timoshenko, Roman;
- Vaneev, Alexander;
- Kolmogorov, Vasilii;
- Savin, Nikita;
- Klyachko, Natalia;
- Barykin, Evgeny;
- Gorbacheva, Lyubov;
- Maksimov, Georgy;
- Kozin, Sergei;
- Erofeev, Alexander;
- Korchev, Yuri;
- Novak, Pavel;
- Edwards, Christopher;
- Majouga, Alexander;
- Makarov, Alexander;
- Gorelkin, Peter
Publication type:
Abstract
Cell stiffness and ROS level alterations in living neurons mediated by β-amyloid oligomers measured by scanning ion-conductance microscopy.
Published in:
2021
By:
- Suchalko, Oleg;
- Timoshenko, Roman;
- Vaneev, Alexander;
- Kolmogorov, Vasilii;
- Savin, Nikita;
- Klyachko, Natalia;
- Barykin, Evgeny;
- Gorbacheva, Lyubov;
- Maksimov, Georgy;
- Kozin, Sergei;
- Erofeev, Alexander;
- Korchev, Yuri;
- Novak, Pavel;
- Edwards, Christopher;
- Majouga, Alexander;
- Makarov, Alexander;
- Gorelkin, Peter
Publication type:
Abstract
Phosphorylation and Dephosphorylation of Beta-Amyloid Peptide in Model Cell Cultures: The Role of Cellular Protein Kinases and Phosphatases.
Published in:
Life (2075-1729), 2023, v. 13, n. 1, p. 147, doi. 10.3390/life13010147
By:
- Barykin, Evgeny P.;
- Yanvarev, Dmitry V.;
- Strelkova, Maria A.;
- Valuev-Elliston, Vladimir T.;
- Varshavskaya, Kseniya B.;
- Mitkevich, Vladimir A.;
- Makarov, Alexander A.
Publication type:
Article
Phosphorylation of the Amyloid-Beta Peptide Inhibits Zinc-Dependent Aggregation, Prevents Na,K-ATPase Inhibition, and Reduces Cerebral Plaque Deposition.
Published in:
Frontiers in Molecular Neuroscience, 2018, p. N.PAG, doi. 10.3389/fnmol.2018.00302
By:
- Barykin, Evgeny P.;
- Petrushanko, Irina Y.;
- Kozin, Sergey A.;
- Telegin, Georgy B.;
- Chernov, Alexander S.;
- Lopina, Olga D.;
- Radko, Sergey P.;
- Mitkevich, Vladimir A.;
- Makarov, Alexander A.
Publication type:
Article
Amyloid β Modification: A Key to the Sporadic Alzheimer's Disease?
Published in:
Frontiers in Genetics, 2017, p. 1, doi. 10.3389/fgene.2017.00058
By:
- Barykin, Evgeny P.;
- Mitkevich, Vladimir A.;
- Kozin, Sergey A.;
- Makarov, Alexander A.
Publication type:
Article
Na,K-ATPase Acts as a Beta-Amyloid Receptor Triggering Src Kinase Activation.
Published in:
Cells (2073-4409), 2022, v. 11, n. 17, p. 2753, doi. 10.3390/cells11172753
By:
- Petrushanko, Irina Yu.;
- Tverskoi, Artem M.;
- Barykin, Evgeny P.;
- Petrovskaya, Aleksandra V.;
- Strelkova, Maria A.;
- Leonova, Olga G.;
- Anashkina, Anastasia A.;
- Tolstova, Anna P.;
- Adzhubei, Alexei A.;
- Bogdanova, Anna Yu.;
- Makarov, Alexander A.;
- Mitkevich, Vladimir A.
Publication type:
Article
Isomerization of Asp7 in Beta-Amyloid Enhances Inhibition of the α7 Nicotinic Receptor and Promotes Neurotoxicity.
Published in:
Cells (2073-4409), 2019, v. 8, n. 8, p. 771, doi. 10.3390/cells8080771
By:
- Barykin, Evgeny P.;
- Garifulina, Alexandra I.;
- Kruykova, Elena V.;
- Spirova, Ekaterina N.;
- Anashkina, Anastasia A.;
- Adzhubei, Alexei A.;
- Shelukhina, Irina V.;
- Kasheverov, Igor E.;
- Mitkevich, Vladimir A.;
- Kozin, Sergey A.;
- Hollmann, Michael;
- Tsetlin, Victor I.;
- Makarov, Alexander A.
Publication type:
Article
Zn-dependent β-amyloid Aggregation and its Reversal by the Tetrapeptide HAEE.
Published in:
Aging & Disease, 2023, v. 14, n. 2, p. 309, doi. 10.14336/AD.2022.0827
By:
- Mitkevich, Vladimir A.;
- Barykin, Evgeny P.;
- Eremina, Svetlana;
- Pani, Bibhusita;
- Katkova-Zhukotskaya, Olga;
- Polshakov, Vladimir I.;
- Adzhubei, Alexei A.;
- Kozin, Sergey A.;
- Mironov, Alexander S.;
- Makarov, Alexander A.;
- Nudler, Evgeny
Publication type:
Article
Post-translational modifications of beta-amyloid alter its transport in the blood-brain barrier in vitro model.
Published in:
Frontiers in Molecular Neuroscience, 2024, p. 1, doi. 10.3389/fnmol.2024.1362581
By:
- Varshavskaya, Kseniya B.;
- Petrushanko, Irina Yu;
- Mitkevich, Vladimir A.;
- Barykin, Evgeny P.;
- Makarov, Alexander A.
Publication type:
Article
Intravenously Injected Amyloid-β Peptide With Isomerized Asp7 and Phosphorylated Ser8 Residues Inhibits Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice Model of Alzheimer’s Disease.
Published in:
Frontiers in Neuroscience, 2018, p. N.PAG, doi. 10.3389/fnins.2018.00518
By:
- Kozin, Sergey A.;
- Barykin, Evgeny P.;
- Telegin, Georgy B.;
- Chernov, Alexander S.;
- Adzhubei, Alexei A.;
- Radko, Sergey P.;
- Mitkevich, Vladimir A.;
- Makarov, Alexander A.
Publication type:
Article

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