We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Circulating tumor DNA in hepatocellular carcinoma: trends and challenges.
- Authors
Jia-Cheng Tang; Yi-Li Feng; Tao Guo; An-Yong Xie; Xiu-Jun Cai
- Abstract
Molecular characterization of individual patients' tumor cells is becoming increasingly important in offering effective treatment for patients in clinical practice. Recent advances in the field have indicated that circulating tumor DNA (ctDNA) has huge potential to serve as a biomarker for early detection and precision treatment as well as prognosis of hepatocellular carcinoma (HCC). As ctDNA in HCC patients harbors the molecular characteristics of HCC tumor cells, ctDNA analysis in the blood may be sufficient for convenient, non-invasive and accurate detection, providing information for HCC diagnosis, treatment and prognosis. In this review, we will summarize and discuss current trends and challenges of ctDNA application in HCC.
- Subjects
DNA analysis; LIVER cancer; GENETICS
- Publication
Cell & Bioscience, 2016, Vol 6, p1
- ISSN
2045-3701
- Publication type
Article
- DOI
10.1186/s13578-016-0100-z