We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Determinants of Postpartum Vitamin D Status in the Caucasian Mother-Offspring Pairs at a Latitude of 52°N: A Cross-Sectional Study.
- Authors
Czech-Kowalska, Justyna; Gruszfeld, Dariusz; Jaworski, Maciej; Bulsiewicz, Dorota; Latka-Grot, Julita; Pleskaczynska, Agata; Lygas, Justyna; Wygledowska, Grazyna; Pawlus, Beata; Zochowska, Anna; Borszewska-Kornacka, Maria K.; Dobrzanska, Anna
- Abstract
Background: High prevalence of vitamin D deficiency in pregnancy is recorded. Aim: To establish determinants of postpartum 25-hydroxyvitamin D (25(OH)D) levels on mothers and offspring. Methods: 25(OH)D level was measured in cord blood and maternal blood collected ≤3 weeks postpartum. Maternal socioeconomic status, vitamin D intake, sun exposure during pregnancy and maternal and neonatal fat mass (FM; dual X-ray absorptiometry) were assessed within 3 weeks postpartum. Results: A total of 174 mother-offspring pairs were enrolled. Maternal 25(OH)D <20 ng/ml was seen in 32 (51%) of summer and 82 (74%) of winter deliveries. Women with 25(OH)D <20 ng/ml had a 2-fold lower percentage of vitamin D intake of ≥800 IU/day than women with 25(OH)D ≥20 ng/ml (p = 0.02). FM (%) was comparable between groups (p > 0.05). Multiple regression analysis revealed the delivery season, prenatal vitamin D intake ≥800 IU/day and duration of supplementation to be the determinants of maternal 25(OH)D level (R2 = 0.26, p < 0.001). Maternal 25(OH)D level, season of birth and duration of maternal supplementation explained 83% of the variance in cord blood 25(OH)D level (R2 = 0.83, p < 0.001). Conclusions: The key determinants of higher maternal vitamin D status were the summer-autumn season of delivery and prenatal use of ≥800 IU/day of vitamin D. The cord blood 25(OH)D level was mainly determined by maternal 25(OH)D level and season of birth. © 2015 S. Karger AG, Basel
- Subjects
POLAND; VITAMIN D deficiency; ACADEMIC medical centers; CHI-squared test; STATISTICAL correlation; FISHER exact test; MOTHER-child relationship; MULTIVARIATE analysis; REGRESSION analysis; RESEARCH funding; STATISTICS; VITAMIN D; DATA analysis; BODY mass index; CROSS-sectional method; DATA analysis software; DESCRIPTIVE statistics; PHOTON absorptiometry; MANN Whitney U Test; CHILDREN; PREGNANCY; PREVENTION
- Publication
Annals of Nutrition & Metabolism, 2015, Vol 67, Issue 1, p33
- ISSN
0250-6807
- Publication type
Article
- DOI
10.1159/000437099