We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Systems biology of lipid metabolism: From yeast to human
- Authors
Nielsen, Jens
- Abstract
Abstract: Lipid metabolism is highly relevant as it plays a central role in a number of human diseases. Due to the highly interactive structure of lipid metabolism and its regulation, it is necessary to apply a holistic approach, and systems biology is therefore well suited for integrated analysis of lipid metabolism. In this paper it is demonstrated that the yeast Saccharomyces cerevisiae serves as an excellent model organism for studying the regulation of lipid metabolism in eukaryotes as most of the regulatory structures in this part of the metabolism are conserved between yeast and mammals. Hereby yeast systems biology can assist to improve our understanding of how lipid metabolism is regulated.
- Subjects
LIPID metabolism; SYSTEMS biology; YEAST; METABOLIC regulation; MAMMALS; SACCHAROMYCES cerevisiae; BIOLOGICAL models
- Publication
FEBS Letters, 2009, Vol 583, Issue 24, p3905
- ISSN
0014-5793
- Publication type
Article
- DOI
10.1016/j.febslet.2009.10.054