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- Title
Validation and clinical feasibility of nitrogen washin/washout functional residual capacity measurements in children.
- Authors
OLEGÅRD, C.; SØNDERGAARD, S.; PÅLSSON, J.; LUNDIN, S.; STENQVIST, O.
- Abstract
Background: The functional residual capacity (FRC) is an important parameter in pediatric respiratory monitoring but it is difficult to assess in the clinical setting. We have introduced a modified N2 washout method utilizing a change of FIO2 of 0.1 for FRC measurement in adult respiratory monitoring. This study validated the algorithm in a pediatric lung model and investigated the stability and feasibility in a pediatric peri-operative and intensive care setting. Methods: The lung model was ventilated in combinations of ventilatory modes, CO2 production, model FRC and respiratory rates. Sixteen children from 10 days to 5 years were studied peri-operatively with controlled ventilation using a Mapleson D system and in the intensive care unit using a Servo-i ventilator in a supported spontaneous mode. FRC was measured during stable metabolic, respiratory and circulatory periods at positive end expiratory pressure of 3–4 and 7–8 cmH2O. Results: In the model and in the clinical setting, we found an excellent agreement between washout and washin measurements of FRC as well as acceptable coefficients of repeatability. Conclusion: FRC was satisfactorily measured by a modified N2 algorithm and may be included as a monitoring variable in pediatric respiratory care. Pediatric FRC monitoring demands strictly stable conditions as measurements are performed close to the limits of the monitor's specifications.
- Subjects
NITROGEN; FUNCTIONAL residual capacity (Respiration); CRITICAL care medicine; LUNGS; INTENSIVE care units; CHILD care
- Publication
Acta Anaesthesiologica Scandinavica, 2010, Vol 54, Issue 3, p370
- ISSN
0001-5172
- Publication type
Article
- DOI
10.1111/j.1399-6576.2009.02107.x