We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Nickel-Catalyzed N-Alkylation of Acylhydrazines and Arylamines Using Alcohols and Enantioselective Examples.
- Authors
Yang, Peng; Zhang, Caili; Ma, Yu; Zhang, Caiyun; Li, Aijie; Tang, Bo; Zhou, Jianrong Steve
- Abstract
A borrowing-hydrogen reaction between amines and alcohols is an atom-economic way to prepare alkylamines, ideally with water as the sole byproduct. Herein, nickel catalysts are used for direct N-alkylation of hydrazides and arylamines using racemic alcohols. Moreover, a nickel catalyst of ( S)-binapine was used for an asymmetric N-alkylation of benzohydrazide with racemic benzylic alcohols.
- Subjects
NICKEL catalysts; ALKYLATION; HYDRAZINE; AROMATIC amines; ALCOHOL; ENANTIOSELECTIVE catalysis
- Publication
Angewandte Chemie, 2017, Vol 129, Issue 46, p14894
- ISSN
0044-8249
- Publication type
Article
- DOI
10.1002/ange.201708949