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- Title
3D black-blood 3T-MRI for the diagnosis of abdominal large vessel vasculitis.
- Authors
Maurus, Stefan; Sommer, Nora N.; Kooijman, Hendrik; Coppenrath, Eva; Witt, Matthias; Schulze-Koops, Hendrik; Czihal, Michael; Hoffmann, Ulrich; Saam, Tobias; Treitl, Karla M.
- Abstract
<bold>Objectives: </bold>To assess the value of a T1-3D black-blood turbo spin echo (TSE) sequence for the diagnosis of abdominal large vessel vasculitis (LVV).<bold>Materials and Methods: </bold>The study included 20 patients with abdominal LVV and 17 controls, who underwent a 3T-MRI scan using a modified T1-3D volumetric isotropic TSE acquisition and a segmented T1-3D turbo field echo sequence (T1-mVISTA/T1-eTHRIVE). Two radiologists independently analyzed the aorta for concentric contrast enhancement, concentric wall thickening, image quality, and flow artifact intensity (CCE/CWT/IQ/FAI; 4-point scales). The mean aortic wall thickness (MAWT) in post-contrast T1-mVISTA was compared between patients and controls.<bold>Results: </bold>IQ of T1-mVISTA was rated good to excellent in 91.5% of 282 evaluated vessel segments with no or minor FAI present in 85.5%. The inter-observer reproducibility for the identification of CCE/CWT on T1-mVISTA was 0.92 and 0.93 (p < 0.001). The distribution of segmental inflammation in T1-mVISTA significantly correlated with T1-eTHRIVE (CCE, κ = 0.768; CWT, κ = 0.715; p < 0.001), resulting in a sensitivity, specificity, and positive predictive value of 100%, 81.3%, and 83.3%. The MAWT significantly differed between patients and controls (3.29 ± 0.81 vs. 2.24 ± 0.45 mm; p < 0.001).<bold>Conclusions: </bold>T1-mVISTA enables the evaluation of the MAWT and allows the detection of abdominal LVV.<bold>Key Points: </bold>• 3D T1w-mVISTA accurately depicted the large abdominal vessels. • 3D T1w-mVISTA enables accurate measurements of the abdominal aortic wall thickness. • 3D T1w-mVISTA is useful for the detection of abdominal LVV.
- Subjects
ECHO-planar imaging; TAKAYASU arteritis; ABDOMINAL wall; VASCULITIS; THREE-dimensional imaging; RESEARCH evaluation; AORTIC diseases; ABDOMINAL aorta; MAGNETIC resonance imaging; MEDICAL artifacts; ABDOMEN
- Publication
European Radiology, 2020, Vol 30, Issue 2, p1041
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-019-06432-0