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- Title
Nephrotoxicity in bone marrow transplant recipients receiving aminoglycoside plus cyclosporine or aminoglycoside alone.
- Authors
Chandrasekar, Pranatharthi H.; Cronin, Simon M.; Chandrasekar, P H; Cronin, S M
- Abstract
We performed a retrospective analysis of the medical records of allogeneic bone marrow transplantation (BMT) patients receiving cyclosporine plus an aminoglycoside and autologous BMT patients receiving an aminoglycoside without concurrent cyclosporine in the immediate post-transplant period. Acute nephrotoxicity was not seen in anyof the patients. Concomitantly used agents such as acyclovir, vanco mycin and amphotericin did not worsen renal function. The present study suggests that aminoglycosides, if carefully monitored, can be safely combined with continu ous infusion of cyclosporine without excessive nephrotoxicity.
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 1991, Vol 27, Issue 6, p845
- ISSN
0305-7453
- Publication type
journal article