We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
CD4CD8αα Lymphocytes, A Novel Human Regulatory T Cell Subset Induced by Colonic Bacteria and Deficient in Patients with Inflammatory Bowel Disease.
- Authors
Sarrabayrouse, Guillaume; Bossard, Céline; Chauvin, Joe-Marc; Jarry, Anne; Meurette, Guillaume; Quévrain, Elodie; Bridonneau, Chantal; Preisser, Laurence; Asehnoune, Karim; Labarrière, Nathalie; Altare, Frédéric; Sokol, Harry; Jotereau, Francine
- Abstract
: Gut bacterium Faecalibacterium prausnitzii activates a newly identified set of human IL-10-producing Treg cells (CD4CD8αα lymphocytes), revealing a mechanism by which commensal microbes contribute to host immunity.
- Subjects
INFLAMMATORY bowel diseases; LYMPHOCYTES; LEUCOCYTES; CROHN'S disease; IMMUNITY
- Publication
PLoS Biology, 2014, Vol 12, Issue 4, p1
- ISSN
1544-9173
- Publication type
Article
- DOI
10.1371/journal.pbio.1001833