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- Title
Utilization of Engineering Advances for Detailed Biomechanical Characterization of the Mitral–Ventricular Relationship to Optimize Repair Strategies: A Comprehensive Review.
- Authors
van Kampen, Antonia; Morningstar, Jordan E.; Goudot, Guillaume; Ingels, Neil; Wenk, Jonathan F.; Nagata, Yasufumi; Yaghoubian, Koushiar M.; Norris, Russell A.; Borger, Michael A.; Melnitchouk, Serguei; Levine, Robert A.; Jensen, Morten O.
- Abstract
The geometrical details and biomechanical relationships of the mitral valve–left ventricular apparatus are very complex and have posed as an area of research interest for decades. These characteristics play a major role in identifying and perfecting the optimal approaches to treat diseases of this system when the restoration of biomechanical and mechano-biological conditions becomes the main target. Over the years, engineering approaches have helped to revolutionize the field in this regard. Furthermore, advanced modelling modalities have contributed greatly to the development of novel devices and less invasive strategies. This article provides an overview and narrative of the evolution of mitral valve therapy with special focus on two diseases frequently encountered by cardiac surgeons and interventional cardiologists: ischemic and degenerative mitral regurgitation.
- Subjects
MITRAL valve; MITRAL valve insufficiency; ENGINEERING; CARDIOLOGISTS
- Publication
Bioengineering (Basel), 2023, Vol 10, Issue 5, p601
- ISSN
2306-5354
- Publication type
Article
- DOI
10.3390/bioengineering10050601