We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Anti-UV Microgel Based on Interfacial Polymerization to Decrease Skin Irritation of High Permeability UV Absorber Ethylhexyl Methoxycinnamate.
- Authors
Wang, Wei; He, Qi-Tong; Chen, Yin-Feng; Wang, Bai-Hui; Xu, Wen-Ying; Liu, Qing-Lei; Liu, Hui-Min
- Abstract
Ethylhexyl methoxycinnamate (EHMC) is frequently employed as a photoprotective agent in sunscreen formulations. EHMC has been found to potentially contribute to health complications as a result of its propensity to produce irritation and permeate the skin. A microgel carrier, consisting of poly(ethylene glycol dimethacrylate) (pEDGMA), was synthesized using interfacial polymerization with the aim of reducing the irritation and penetration of EHMC. The thermogravimetric analysis (TGA) indicated that the EHMC content accounted for 75.72% of the total composition. Additionally, the scanning electron microscopy (SEM) images depicted the microgel as exhibiting a spherical morphology. In this study, the loading of EHMC was demonstrated through FTIR and contact angle tests. The UV resistance, penetration, and skin irritation of the EHMC-pEDGMA microgel were additionally assessed. The investigation revealed that the novel sunscreen compound, characterized by limited dermal absorption, had no irritant effects and offered sufficient protection against ultraviolet radiation.
- Subjects
POLYMERIZATION; SKIN permeability; SKIN absorption; SUNSCREENS (Cosmetics); ETHYLENE glycol derivatives
- Publication
Gels (2310-2861), 2024, Vol 10, Issue 3, p177
- ISSN
2310-2861
- Publication type
Article
- DOI
10.3390/gels10030177