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- Title
血清 CRP, PCT, 脂肪酶与胰腺炎分型及预后的相关性研究.
- Authors
王丽萍; 苏秉忠; 丛春莉; 王宏霞; 刘彦琦
- Abstract
Objective: To investigate the correlation of serum CRP, PCT and lipase levels with the classification and prognosis of pancreatitis. Methods: 87 cases of patients with acute pancreatitis, including, 65 cases of light acute pancreatitis, and 22 cases of severe acute pancreatitis. At1 d, 3 d, 7 d, 14 d after admission, the levels of serum CRP, PCT and lipase were detected, and the APACHEII scores were calculated. Compare and analyze the differences of CRP and PCT, lipase and APACHEII score at different time points between the two groups. Multiple linear regression was applied to analyze the risk factors of the prognosis of acute pancreatitis. Results: The severe degree of acute pancreatitis had a correlation with diabetes, history of drinking and gallstone lithiasis (P<0.05). The CRP and PCT level at 1 d, 3 d had no statistical difference between light group and severe group (P>0.05), but at 7 d and 14 d, they were statistically different between the two groups (P<0.05). The lipase levels at 3 d, 7 d and 14 d also had statistical difference between the two groups (P<0.05). The APACH EII score also statistically significant difference at 1 d, 3 d, 7 d and 14 d (P<0.05). Regression equation: Logit P=0.0017× PCT+0.0297× history of gallstone calculi+0.093× APACHEII score-0.193. Conclusion: The diabetes and gallstone calculi were associated with severe acute pancreatitis. PCT level and APACHEII scores keeping in a high level indicated a poor prognosis of acute pancreatitis.
- Publication
Progress in Modern Biomedicine, 2017, Vol 17, Issue 7, p1739
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2017.09.038