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- Title
Successful Treatment of Mycoplasma hominis Meningitis, Diagnosed Using Real-Time Polymerase Chain Reaction, with Ciprofloxacin in a Neonate.
- Authors
Iktae Gwon; Woo Sun Song; Yong-Hak Sohn; Seung Yeon Kim
- Abstract
Mycoplasma hominis can cause life-threatening central nervous system infections in neonates following intrauterine infection or during delivery. In newborns, the diagnosis and treatment of M. hominis meningitis are challenging, because cultures are often negative and the bacterium is not susceptible to empirical antibiotics. Herein, we describe a case of neonatal M. hominis meningitis diagnosed using real-time polymerase chain reaction (RT-PCR) and treated with ciprofloxacin. The patient was a 3-day-old female hospitalized for a fever and lethargy. Her blood laboratory findings were non-specific; cerebrospinal fluid (CSF) examination showed a white blood cell count of 580/µL and indicated meningitis. Her symptoms could not be controlled with empirical antibiotics. Urine culture on a special medium revealed ciprofloxacinsusceptible M. hominis. Furthermore, the RT-PCR performed with the CSF sample revealed M. hominis. Therefore, the patient was administered ciprofloxacin; after 2 days, the fever subsided. The patient was discharged on day 30 without complications.
- Subjects
POLYMERASE chain reaction; CENTRAL nervous system infections; MENINGITIS; LEUKOCYTE count; MYCOPLASMA; MYCOPLASMA pneumoniae infections
- Publication
Neonatal Medicine, 2020, Vol 27, Issue 3, p147
- ISSN
2287-9412
- Publication type
Article
- DOI
10.5385/nm.2020.27.3.147