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- Title
Introduction to systematic reviews and meta-analysis.
- Authors
Wolfe, Rory; Abramson, Michael; McKenzie, Joanne E.; Beller, Elaine M.; Forbes, Andrew B.
- Abstract
Systematic reviews provide a method for collating and synthesizing research, and are used to inform healthcare decision making by clinicians, consumers and policy makers. A core component of many systematic reviews is a meta-analysis, which is a statistical synthesis of results across studies. In this review article, we introduce meta-analysis, focusing on the different meta-analysis models, their interpretation, how a model should be selected and discuss potential threats to the validity of meta-analyses. We illustrate the application of meta-analysis using data from a review examining the effects of early use of inhaled corticosteroids in the emergency department treatment of acute asthma.
- Subjects
SYSTEMATIC reviews; META-analysis; ASTHMA treatment; ADRENOCORTICAL hormones; HEALTH policy
- Publication
Respirology, 2016, Vol 21, Issue 4, p626
- ISSN
1323-7799
- Publication type
Article
- DOI
10.1111/resp.12783