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Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients. Dose-response effects of insulin on glucose turnover.
Published in:
1996
By:
- Christiansen E;
- Vestergaard H;
- Tibell A;
- Hother-Nielsen O;
- Holst JJ;
- Pedersen O;
- Madsbad S;
- Christiansen, E;
- Vestergaard, H;
- Tibell, A;
- Hother-Nielsen, O;
- Holst, J J;
- Pedersen, O;
- Madsbad, S
Publication type:
journal article
The effect of glucagon-like peptide I (GLP-I) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones.
Published in:
1996
By:
- Toft-Nielsen M;
- Madsbad S;
- Holst JJ;
- Toft-Nielson, M;
- Madsbad, S;
- Holst, J J
Publication type:
journal article
Dual-hormone treatment with insulin and glucagon in patients with type 1 diabetes.
Published in:
2015
By:
- Reiband, H. K.;
- Schmidt, S.;
- Ranjan, A.;
- Holst, J. J.;
- Madsbad, S.;
- Nørgaard, K.
Publication type:
journal article
Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene–gene interaction.
Published in:
Diabetologia, 2009, v. 52, n. 7, p. 1308, doi. 10.1007/s00125-009-1362-3
By:
- Sparsø, T.;
- Grarup, N.;
- Andreasen, C.;
- Albrechtsen, A.;
- Holmkvist, J.;
- Andersen, G.;
- Jørgensen, T.;
- Borch-Johnsen, K.;
- Sandbæk, A.;
- Lauritzen, T.;
- Madsbad, S.;
- Hansen, T.;
- Pedersen, O.
Publication type:
Article
The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.
Published in:
Diabetologia, 2009, v. 52, n. 7, p. 1298, doi. 10.1007/s00125-009-1307-x
By:
- Pilgaard, K.;
- Jensen, C.;
- Schou, J.;
- Lyssenko, V.;
- Wegner, L.;
- Brøns, C.;
- Vilsbøll, T.;
- Hansen, T.;
- Madsbad, S.;
- Holst, J.;
- Vølund, A.;
- Poulsen, P.;
- Groop, L.;
- Pedersen, O.;
- Vaag, A.
Publication type:
Article
The proposed terminology ‘A<sub>1c</sub>-derived average glucose’ is inherently imprecise and should not be adopted. Reply to Bloomgarden ZT, Inzucchi SE, Karnieli E, et al. [letter].
Published in:
2009
By:
- Haugaard, S.;
- Madsbad, S.;
- Mølvig, J.
Publication type:
Letter
Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes.
Published in:
Diabetologia, 2009, v. 52, n. 2, p. 199, doi. 10.1007/s00125-008-1195-5
By:
- Højberg, P.;
- Vilsbøll, T.;
- Rabøl, R.;
- Knop, F.;
- Bache, M.;
- Krarup, T.;
- Holst, J.;
- Madsbad, S.
Publication type:
Article
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.
Published in:
Diabetologia, 2008, v. 51, n. 9, p. 1646, doi. 10.1007/s00125-008-1064-2
By:
- Sparsø, T.;
- Andersen, G.;
- Albrechtsen, A.;
- Jørgensen, T.;
- Borch-Johnsen, K.;
- Sandbæk, A.;
- Lauritzen, T.;
- Wasson, J.;
- Permutt, M.;
- Glaser, B.;
- Madsbad, S.;
- Pedersen, O.;
- Hansen, T.
Publication type:
Article
Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes.
Published in:
Diabetologia, 2008, v. 51, n. 4, p. 632, doi. 10.1007/s00125-008-0943-x
By:
- Højberg, P.;
- Zander, M.;
- Vilsbøll, T.;
- Knop, F.;
- Krarup, T.;
- Vølund, A.;
- Holst, J.;
- Madsbad, S.
Publication type:
Article
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.
Published in:
2008
By:
- Sparsø, T.;
- Andersen, G.;
- Nielsen, T.;
- Burgdorf, K.;
- Gjesing, A.;
- Nielsen, A.;
- Albrechtsen, A.;
- Rasmussen, S.;
- Jørgensen, T.;
- Borch-Johnsen, K.;
- Sandbæk, A.;
- Lauritzen, T.;
- Madsbad, S.;
- Hansen, T.;
- Pedersen, O.
Publication type:
Correction Notice
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.
Published in:
Diabetologia, 2008, v. 51, n. 1, p. 70, doi. 10.1007/s00125-007-0865-z
By:
- Sparsø, T.;
- Andersen, G.;
- Nielsen, T.;
- Burgdorf, K.;
- Gjesing, A.;
- Nielsen, A.;
- Albrechtsen, A.;
- Rasmussen, S.;
- Jørgensen, T.;
- Borch-Johnsen, K.;
- Sandbæk, A.;
- Lauritzen, T.;
- Madsbad, S.;
- Hansen, T.;
- Pedersen, O.
Publication type:
Article
Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus.
Published in:
Diabetologia, 2007, v. 50, n. 4, p. 797, doi. 10.1007/s00125-006-0566-z
By:
- Knop, F.;
- Vilsbøll, T.;
- Madsbad, S.;
- Holst, J.;
- Krarup, T.
Publication type:
Article
The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes.
Published in:
Diabetologia, 2006, v. 49, n. 2, p. 369, doi. 10.1007/s00125-005-0098-y
By:
- Zander, M.;
- Madsbad, S.;
- Deacon, C.;
- Holst, J.
Publication type:
Article
Low birthweight is associated with specific changes in muscle insulin-signalling protein expression.
Published in:
Diabetologia, 2005, v. 48, n. 3, p. 547, doi. 10.1007/s00125-005-1669-7
By:
- Ozanne, S. E.;
- Jensen, C. B.;
- Tingey, K. J.;
- Storgaard, H.;
- Madsbad, S.;
- Vaag, A. A.
Publication type:
Article
No interactions between polymorphisms in the β<sub>3</sub>-adrenergic receptor gene and the PPAR-γ gene on the risk of the insulin resistance syndrome in the Danish MONICA cohort L. Frederiksen et al.: Polymorphisms, interactions and the insulin resistance syndrome
Published in:
Diabetologia, 2003, v. 46, n. 5, p. 729, doi. 10.1007/s00125-003-1092-x
By:
- Frederiksen, L.;
- Brødbaek, K.;
- Fenger, M.;
- Madsbad, S.;
- Urhammer, S.A.;
- Jørgensen, T.;
- Borch-Johnsen, K.
Publication type:
Article
Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients T. Vilsbøll et al.: Defective insulin response to GIP in Type II diabetes.
Published in:
Diabetologia, 2002, v. 45, n. 8, p. 1111, doi. 10.1007/s00125-002-0878-6
By:
- Vilsb&ostrok;ll, T.;
- Krarup, T.;
- Madsbad, S.;
- Holst, J.
Publication type:
Article
Quantification of beta-cell function during IVGTT in Type II and non-diabetic subjects: assessment of insulin secretion by mathematical methods.
Published in:
Diabetologia, 2001, v. 44, n. 10, p. 1339, doi. 10.1007/s001250100639
By:
- Kjems, L. L.;
- Vølund, A.;
- Madsbad, S.
Publication type:
Article
Obesity - an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential.
Published in:
Obesity Reviews, 2011, v. 12, n. 8, p. 593, doi. 10.1111/j.1467-789X.2011.00860.x
By:
- Torekov, S. S.;
- Madsbad, S.;
- Holst, J. J.
Publication type:
Article
An overview of once-weekly glucagon-like peptide-1 receptor agonists-available efficacy and safety data and perspectives for the future.
Published in:
Diabetes, Obesity & Metabolism, 2011, v. 13, n. 5, p. 394, doi. 10.1111/j.1463-1326.2011.01357.x
By:
- Madsbad, S.;
- Kielgast, U.;
- Asmar, M.;
- Deacon, C. F.;
- Torekov, S. S.;
- Holst, J. J.
Publication type:
Article
Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes.
Published in:
Diabetes, Obesity & Metabolism, 2010, v. 12, n. 9, p. 806, doi. 10.1111/j.1463-1326.2010.01237.x
By:
- Rabøl, R.;
- Boushel, R.;
- Almdal, T.;
- Hansen, C. N.;
- Ploug, T.;
- Haugaard, S. B.;
- Prats, C.;
- Madsbad, S.;
- Dela, F.
Publication type:
Article
Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus.
Published in:
Diabetes, Obesity & Metabolism, 2010, v. 12, n. 4, p. 323, doi. 10.1111/j.1463-1326.2009.01167.x
By:
- Aaboe, K.;
- Knop, F. K.;
- Vilsbøll, T.;
- Deacon, C. F.;
- Holst, J. J.;
- Madsbad, S.;
- Krarup, T.
Publication type:
Article
Study rationale and design of the CIMT trial: The Copenhagen Insulin and Metformin Therapy Trial.
Published in:
Diabetes, Obesity & Metabolism, 2009, v. 11, n. 4, p. 315, doi. 10.1111/j.1463-1326.2008.00959.x
By:
- Christensen, L. Lundby;
- Almdal, T.;
- Boesgaard, T.;
- Breum, L.;
- Dunn, E.;
- Gade-Rasmussen, B.;
- Gluud, C.;
- Hedetoft, C.;
- Jarloev, A.;
- Jensen, T.;
- Krarup, T.;
- Johansen, L. B.;
- Lund, S. S.;
- Madsbad, S.;
- Mathiesen, E.;
- Moelvig, J.;
- Nielsen, F.;
- Perrild, H.;
- Pedersen, O.;
- Roeder, M.
Publication type:
Article
Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes.
Published in:
Diabetes, Obesity & Metabolism, 2009, v. 11, n. 4, p. 355, doi. 10.1111/j.1463-1326.2008.00977.x
By:
- Rabøl, R.;
- Højberg, P. M. V.;
- Almdal, T.;
- Boushel, R.;
- Haugaard, S. B.;
- Madsbad, S.;
- Dela, F.
Publication type:
Article
Patient-reported rating of gastrointestinal adverse effects during treatment of type 2 diabetes with the once-daily human GLP-1 analogue, liraglutide.
Published in:
2008
By:
- Horowitz, M.;
- Vilsbøll, T.;
- Zdravkovic, M.;
- Hammer, M.;
- Madsbad, S.
Publication type:
Letter
Minor long-term changes in weight have beneficial effects on insulin sensitivity and β-cell function in obese subjects.
Published in:
Diabetes, Obesity & Metabolism, 2002, v. 4, n. 1, p. 19, doi. 10.1046/j.1463-1326.2002.00161.x
By:
- Rosenfalck, A. M.;
- Hendel, H.;
- Rasmussen, M. H.;
- Almdal, T.;
- Andersen, T.;
- Hilsted, J.;
- Madsbad, S.
Publication type:
Article
Glycaemic control and suppressor cell activity in patients with insulin-dependent diabetes mellitus.
Published in:
Clinical & Experimental Immunology, 1982, v. 48, n. 1, p. 189
By:
- Buschard, K.;
- Madsbad, S.;
- Krarup, T.;
- Rygaard, J.
Publication type:
Article
Depressed suppressor cell activity in patients with newly diagnosed insulin-dependent diabetes mellitus.
Published in:
Clinical & Experimental Immunology, 1980, v. 41, n. 1, p. 25
By:
- Buschard, K.;
- Madsbad, S.;
- Rygaard, J.
Publication type:
Article
Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass.
Published in:
Diabetologia, 2012, v. 55, n. 7, p. 1890, doi. 10.1007/s00125-012-2556-7
By:
- Dirksen, C.;
- Jørgensen, N.;
- Bojsen-Møller, K.;
- Jacobsen, S.;
- Hansen, D.;
- Worm, D.;
- Holst, J.;
- Madsbad, S.
Publication type:
Article
Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes.
Published in:
Diabetologia, 2012, v. 55, n. 5, p. 1406, doi. 10.1007/s00125-012-2459-7
By:
- Jensen, D.;
- Aaboe, K.;
- Henriksen, J.;
- Vølund, A.;
- Holst, J.;
- Madsbad, S.;
- Krarup, T.
Publication type:
Article
Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration.
Published in:
Diabetologia, 2012, v. 55, n. 2, p. 443, doi. 10.1007/s00125-011-2340-0
By:
- Larsen, S.;
- Rabøl, R.;
- Hansen, C.;
- Madsbad, S.;
- Helge, J.;
- Dela, F.
Publication type:
Article
Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals.
Published in:
Diabetologia, 2012, v. 55, n. 1, p. 105, doi. 10.1007/s00125-011-2320-4
By:
- Burgdorf, K.;
- Gjesing, A.;
- Grarup, N.;
- Justesen, J.;
- Sandholt, C.;
- Witte, D.;
- Jørgensen, T.;
- Madsbad, S.;
- Hansen, T.;
- Pedersen, O.
Publication type:
Article
Homozygous carriers of the G allele of rs4664447 of the glucagon gene ( GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1.
Published in:
Diabetologia, 2011, v. 54, n. 11, p. 2820, doi. 10.1007/s00125-011-2265-7
By:
- Torekov, S.;
- Ma, L.;
- Grarup, N.;
- Hartmann, B.;
- Hainerová, I.;
- Kielgast, U.;
- Kissow, H.;
- Rosenkilde, M.;
- Lebl, J.;
- Witte, D.;
- Jørgensen, T.;
- Sandbaek, A.;
- Lauritzen, T.;
- Madsen, O.;
- Wang, J.;
- Linneberg, A.;
- Madsbad, S.;
- Holst, J.;
- Hansen, T.;
- Pedersen, O.
Publication type:
Article
Retinal function in relation to improved glycaemic control in type 1 diabetes.
Published in:
Diabetologia, 2011, v. 54, n. 7, p. 1853, doi. 10.1007/s00125-011-2149-x
By:
- Holfort, S.;
- Nørgaard, K.;
- Jackson, G.;
- Hommel, E.;
- Madsbad, S.;
- Munch, I.;
- Klemp, K.;
- Sander, B.;
- Larsen, M.
Publication type:
Article
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Published in:
Diabetologia, 2011, v. 54, n. 6, p. 1427, doi. 10.1007/s00125-011-2098-4
By:
- Larsen, S.;
- Stride, N.;
- Hey-Mogensen, M.;
- Hansen, C.;
- Andersen, J.;
- Madsbad, S.;
- Worm, D.;
- Helge, J.;
- Dela, F.
Publication type:
Article
Clinical use of the co-formulation of insulin degludec and insulin aspart.
Published in:
2016
By:
- Kumar, A.;
- Awata, T.;
- Bain, S. C.;
- Ceriello, A.;
- Fulcher, G. R.;
- Unnikrishnan, A. G.;
- Arechavaleta, R.;
- Gonzalez‐Gálvez, G.;
- Hirose, T.;
- Home, P. D.;
- Kaku, K.;
- Litwak, L.;
- Madsbad, S.;
- Pinget, M.;
- Mehta, R.;
- Mithal, A.;
- Tambascia, M.;
- Tibaldi, J.;
- Christiansen, J.S.
Publication type:
journal article
Nutrient re-routing and altered gut-islet cell crosstalk may explain early relief of severe postprandial hypoglycaemia after reversal of Roux-en-Y gastric bypass.
Published in:
Diabetic Medicine, 2017, v. 34, n. 12, p. 1783, doi. 10.1111/dme.13443
By:
- Svane, M. S.;
- Toft‐Nielsen, M. B.;
- Kristiansen, V. B.;
- Hartmann, B.;
- Holst, J. J.;
- Madsbad, S.;
- Bojsen‐Møller, K. N.
Publication type:
Article
Efficacy and safety of dipeptidyl peptidase-4 inhibitors as an add-on to insulin treatment in patients with Type 2 diabetes: a review.
Published in:
Diabetic Medicine, 2014, v. 31, n. 11, p. 1293, doi. 10.1111/dme.12561
By:
- Frandsen, C. S. S.;
- Madsbad, S.
Publication type:
Article
The immune marker soluble urokinase plasminogen activator receptor is associated with new-onset diabetes in non-smoking women and men.
Published in:
Diabetic Medicine, 2012, v. 29, n. 4, p. 479, doi. 10.1111/j.1464-5491.2011.03513.x
By:
- Haugaard, S. B.;
- Andersen, O.;
- Hansen, T. W.;
- Eugen-Olsen, J.;
- Linneberg, A.;
- Madsbad, S.;
- Olsen, M. H.;
- Jørgensen, T.;
- Borch-Johnsen, K.;
- Jeppesen, J.
Publication type:
Article
Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes.
Published in:
2008
By:
- Højberg PV;
- Vilsbøll T;
- Zander M;
- Knop FK;
- Krarup T;
- Vølund A;
- Holst JJ;
- Madsbad S
Publication type:
Journal Article
Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes.
Published in:
Diabetic Medicine, 2008, v. 25, n. 11, p. 1268, doi. 10.1111/j.1464-5491.2008.02579.x
By:
- Højberg, P. V.;
- Vilsbøll, T.;
- Zander, M.;
- Knop, F. K.;
- Krarup, T.;
- Vølund, A.;
- Holst, J. J.;
- Madsbad, S.
Publication type:
Article
Beneficial effects of once-daily liraglutide, a human glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patients with Type 2 diabetes.
Published in:
2008
By:
- Courrèges J;
- Vilsbøll T;
- Zdravkovic M;
- Le-Thi T;
- Krarup T;
- Schmitz O;
- Verhoeven R;
- Bugáñová I;
- Madsbad S
Publication type:
Journal Article
Beneficial effects of once-daily liraglutide, a human glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patients with Type 2 diabetes.
Published in:
2008
By:
- Courrèges, J.-P.;
- Vilsbøll, T.;
- Zdravkovic, M.;
- Le-Thi, T.;
- Krarup, T.;
- Schmitz, O.;
- Verhoeven, R.;
- Bugáñov, I.;
- Madsbad, S.
Publication type:
Letter
Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with Type 2 diabetes mellitus.
Published in:
2008
By:
- Vilsbøll T;
- Brock B;
- Perrild H;
- Levin K;
- Lervang HH;
- Kølendorf K;
- Krarup T;
- Schmitz O;
- Zdravkovic M;
- Le-Thi T;
- Madsbad S
Publication type:
Journal Article
Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with Type 2 diabetes mellitus.
Published in:
Diabetic Medicine, 2008, v. 25, n. 2, p. 152, doi. 10.1111/j.1464-5491.2007.02333.x
By:
- Vilsbøll, T.;
- Brock, B.;
- Perrild, H.;
- Levin, K.;
- Lervang, H.-H.;
- Kølendorf, K.;
- Krarup, T.;
- Schmitz, O.;
- Zdravkovic, M.;
- Le-Thi, T.;
- Madsbad, S.
Publication type:
Article
A low-fat diet improves peripheral insulin sensitivity in patients with Type 1 diabetes.
Published in:
2006
By:
- Rosenfalck AM;
- Almdal T;
- Viggers L;
- Madsbad S;
- Hilsted J
Publication type:
Journal Article
A low-fat diet improves peripheral insulin sensitivity in patients with Type 1 diabetes.
Published in:
Diabetic Medicine, 2006, v. 23, n. 4, p. 384, doi. 10.1111/j.1464-5491.2005.01810.x
By:
- Rosenfalck, A. M.;
- Almdal, T.;
- Viggers, L.;
- Madsbad, S.;
- Hilsted, J.
Publication type:
Article
Large-scale studies of the Leu72Met polymorphism of the ghrelin gene in relation to the metabolic syndrome and associated quantitative traits.
Published in:
Diabetic Medicine, 2005, v. 22, n. 9, p. 1157, doi. 10.1111/j.1464-5491.2005.01575.x
By:
- Bing, C.;
- Ambye, L.;
- Fenger, M.;
- Jørgensen, T.;
- Borch-Johnsen, K.;
- Madsbad, S.;
- Urhammer, S. A.
Publication type:
Article
Sustained effects of pioglitazone vs. glibenclamide on insulin sensitivity, glycaemic control, and lipid profiles in patients with Type 2 diabetes.
Published in:
Diabetic Medicine, 2004, v. 21, n. 8, p. 859, doi. 10.1111/j.1464-5491.2004.01258.x
By:
- Tan, M. H.;
- Johns, D.;
- Strand, J.;
- Halse, J.;
- Madsbad, S.;
- Eriksson, J. W.;
- Clausen, J.;
- Konkoy, C. S.;
- Herz, M.
Publication type:
Article
Body composition in adults with Type 1 diabetes at onset and during the first year of insulin therapy.
Published in:
Diabetic Medicine, 2002, v. 19, n. 5, p. 417, doi. 10.1046/j.1464-5491.2002.00702.x
By:
- Rosenfalck, A. M;
- Almdal, T;
- Hilsted, J;
- Madsbad, S
Publication type:
Article
Effects of subcutaneous, low‐dose glucagon on insulin‐induced mild hypoglycaemia in patients with insulin pump treated type 1 diabetes.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 4, p. 410, doi. 10.1111/dom.12627
By:
- Nørgaard, K.;
- Ranjan, A.;
- Schmidt, S.;
- Madsbad, S.;
- Holst, J. J.
Publication type:
Article

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