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- Title
Corrigendum: Children and Adults With Mild COVID-19: Dynamics of the Memory T Cell Response Up to 10 Months.
- Authors
Kaaijk, Patricia; Olivo Pimentel, Verónica; Emmelot, Maarten E.; Poelen, Martien C. M.; Cevirgel, Alper; Schepp, Rutger M.; den Hartog, Gerco; Reukers, Daphne F. M.; Beckers, Lisa; van Beek, Josine; van Els, Cécile A. C. M.; Meijer, Adam; Rots, Nynke Y.; de Wit, Jelle
- Abstract
B Results b : Upon stimulation of PBMCs with heat-inactivated SARS-CoV-2 or overlapping peptides of spike (S-SARS-CoV-2) and nucleocapsid proteins, we found S-SARS-CoV-2-specific IFN- T cell responses in infected children (83%) and adults (100%) that were absent in unexposed controls. Keywords: SARS-CoV-2; COVID-19; mild symptoms; children; T cell immunity; adaptive immunity; antibody response; cytokines EN SARS-CoV-2 COVID-19 mild symptoms children T cell immunity adaptive immunity antibody response cytokines 1 13 13 05/04/22 20220429 NES 220429 An author name was incorrectly written as B Martien Poelen b . For all antigenic stimuli used (i.e. S-SARS-CoV-2, overlapping peptides covering nucleocapsid protein (N) of SARS-CoV-2 (N-SARS-CoV-2), or inactivated whole SARS-CoV-2), the moderately ill adults had significantly higher frequencies of IFN- -producing T cells compared to children at T1. Nevertheless, frequencies of SARS-CoV-2-specific T cells circulating in the blood were significantly reduced at 10 months after infection, although migration of memory SARS-CoV-2-specific T cells to peripheral tissues may have taken place.
- Subjects
IMMUNOLOGIC memory; COUGH; TASTE disorders; IMMUNOGLOBULIN M; SARS-CoV-2; ANTIGENS
- Publication
Frontiers in Immunology, 2022, Vol 13, p1
- ISSN
1664-3224
- Publication type
Correction Notice
- DOI
10.3389/fimmu.2022.893720