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- Title
Identification of Hepatocystis species in a macaque monkey in northern Myanmar.
- Authors
Qiaocheng Chang; Xiaodong Sun; Jian Wang; Jigang Yin; Junpeng Song; Shuai Peng; Huijun Lu; Hongning Zhou; Ning Jiang; Qijun Chen
- Abstract
Background: Long-tailed and pig-tailed macaque monkeys are natural hosts of Plasmodium knowlesi, which has been identified as a fifth malaria parasite infecting humans. In this study, we investigated possible infection by this Plasmodium parasite in macaque monkeys using a combination of polymerase chain reaction amplification and sequencing. Methods: Forty-five blood samples were obtained in 2010 from macaques in northern Myanmar near Yunnan Province of China and investigated for possible infection with Plasmodium species using a nested polymerase chain reaction method for amplification of 18S SSU rRNA genes. Results: Positive amplification was obtained from one monkey, and both sequence and phylogenetic analysis indicated that the parasite was of the Hepatocystis species lineage. Conclusion: The results suggest that a combination of polymerase chain reaction amplification and sequence identification would be necessary for detection of Plasmodium knowlesi infection in both humans and its natural hosts.
- Publication
Research & Reports in Tropical Medicine, 2011, Vol 2, p141
- ISSN
1179-7282
- Publication type
Article
- DOI
10.2147/RRTM.S27182