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- Title
Contrasting association of a non-synonymous leptin receptor gene polymorphism with Wegener’s granulomatosis and Churg–Strauss syndrome.
- Authors
Wieczorek, Stefan; Holle, Julia U.; Bremer, Jan P.; Wibisono, David; Moosig, Frank; Fricke, Harald; Assmann, Gunter; Harper, Lorraine; Arning, Larissa; Gross, Wolfgang L.; Epplen, Joerg T.
- Abstract
Objective. There is evidence that the leptin/ghrelin system is involved in T-cell regulation and plays a role in (auto)immune disorders such as SLE, RA and ANCA-associated vasculitides (AAVs). Here, we evaluate the genetic background of this system in WG.
- Subjects
LEPTIN; GHRELIN; GRANULOMATOSIS with polyangiitis; CHURG-Strauss syndrome; VASCULITIS
- Publication
Rheumatology, 2010, Vol 49, Issue 5, p907
- ISSN
1462-0324
- Publication type
Article
- DOI
10.1093/rheumatology/kep420