We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance.
- Authors
Crimmins, N. A.; Martin, L. J.
- Abstract
Adiponectin plays an important role in insulin sensitivity via adiponectin receptor 1 and 2 signalling. To date, six genetic association studies have examined the role of polymorphisms in the adiponectin receptor 1 and 2 genes (ADIPOR1 and ADIPOR2) in insulin resistance and type 2 diabetes. These studies are summarized in this review along with unpublished data from the authors. In addition, these polymorphism studies are used to illustrate some of the potential pitfalls and reasons for poor reproducibility of findings in genetic association studies.
- Subjects
INSULIN resistance; GENES; GENETIC polymorphisms; TYPE 2 diabetes; OBESITY
- Publication
Obesity Reviews, 2007, Vol 8, Issue 5, p419
- ISSN
1467-7881
- Publication type
Article
- DOI
10.1111/j.1467-789X.2007.00348.x