We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Convergent evolution of plant pattern recognition receptors sensing cysteine-rich patterns from three microbial kingdoms.
- Authors
Yang, Yuankun; Steidele, Christina E.; Rössner, Clemens; Löffelhardt, Birgit; Kolb, Dagmar; Leisen, Thomas; Zhang, Weiguo; Ludwig, Christina; Felix, Georg; Seidl, Michael F.; Becker, Annette; Nürnberger, Thorsten; Hahn, Matthias; Gust, Bertolt; Gross, Harald; Hückelhoven, Ralph; Gust, Andrea A.
- Abstract
The Arabidopsis thaliana Receptor-Like Protein RLP30 contributes to immunity against the fungal pathogen Sclerotinia sclerotiorum. Here we identify the RLP30-ligand as a small cysteine-rich protein (SCP) that occurs in many fungi and oomycetes and is also recognized by the Nicotiana benthamiana RLP RE02. However, RLP30 and RE02 share little sequence similarity and respond to different parts of the native/folded protein. Moreover, some Brassicaceae other than Arabidopsis also respond to a linear SCP peptide instead of the folded protein, suggesting that SCP is an eminent immune target that led to the convergent evolution of distinct immune receptors in plants. Surprisingly, RLP30 shows a second ligand specificity for a SCP-nonhomologous protein secreted by bacterial Pseudomonads. RLP30 expression in N. tabacum results in quantitatively lower susceptibility to bacterial, fungal and oomycete pathogens, thus demonstrating that detection of immunogenic patterns by Arabidopsis RLP30 is involved in defense against pathogens from three microbial kingdoms. Plants have evolved pattern-recognition receptors to perceive pathogens. Here, the authors demonstrate that microbial small cysteine-rich proteins are eminent immune targets that led to convergent evolution of distinct immune receptors in plants.
- Subjects
CONVERGENT evolution; ARABIDOPSIS proteins; PLANT evolution; NICOTIANA benthamiana; PEPTIDES; BACTERIAL proteins; PATTERN perception receptors
- Publication
Nature Communications, 2023, Vol 14, Issue 1, p1
- ISSN
2041-1723
- Publication type
Article
- DOI
10.1038/s41467-023-39208-8