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- Title
Acute dyskinesia: A rare adverse effect of oxcarbazepine in epilepsy with neurobehavioral symptoms.
- Authors
Bhargava, Amita; Bhushan, Bharat; Khichar, Subhakaran; Kasundra, Gaurav
- Abstract
We are reporting an 11-year-old female child of febrile partial seizure since age of 3 months and transient neurobehavioral changes of psychic, gelastic semiology since childhood. She had no history of continued febrile seizure, but had 3 admissions for 3 episodes of status epilepticus in last 3 years. She experienced acute generalized dyskinesia (torticollis, oromandibular dystonia, spasmodic dysphonia, right lower limb eversion plantarlexed type feet dystonia) soon after oxcarbazepine (OXC) therapy from last episode of status epilepsy on 15 April 2013 with similar semiology. We failed to explain the considered infectious, non-convulsive state and hyponatremic extra pyramidal syndrome. We used the Naranjo adverse drug reaction probability scale and stopped OXC. After state intravenous diazepam 2nd day, she was starting to improve and over a period of 4 days she was asymptomatic. We shifted on clonazepam, sodium valproate for further. She was asymptomatic until 1 month follow-up.
- Subjects
DYSKINESIAS; SYMPTOMS; SPASMODIC dysphonia; CLONAZEPAM; VALPROIC acid; THERAPEUTICS
- Publication
International Journal of Nutrition, Pharmacology, Neurological Diseases, 2014, Vol 4, Issue 1, p74
- ISSN
2231-0738
- Publication type
Case Study
- DOI
10.4103/2231-0738.124618