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- Title
Effect of Sulfadoxine-Pyrimethamine Resistance on the Efficacy of Intermittent Preventive Therapy for Malaria Control During Pregnancy.
- Authors
ter Kuile, Feiko O.; van Eijk, Annemieke M.; Filler, Scott J.
- Abstract
This article presents a study of the effect of sulfadoxine-pyrimethamine resistance on the efficacy of intermittent preventive therapy for malaria control during pregnancy. Pregnant women are one of the primary targets for malaria. These women are most vulnerable during their first and second pregnancies. Preventive measures for these women usually consist of insecticide treated bed nets and intermittent preventive therapy (IPT) with sulfadoxine-pryimethamine. The IPT therapy consists of the drug given at predefined intervals at least one month apart regardless of the presence of malaria disease. The study found that IPT substantially reduced the bad effects of malaria in pregnancy but warns that increasing resistance to the drug is being seen.
- Subjects
MALARIA treatment; PROTOZOAN diseases; PRENATAL care; INSECTICIDES; DRUG resistance; DRUG resistance in microorganisms; PREVENTIVE medicine
- Publication
JAMA: Journal of the American Medical Association, 2007, Vol 297, Issue 23, p2603
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.297.23.2603