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- Title
Changes in Body Mass Index with Longer-term Integrase Inhibitor Use: A Longitudinal Analysis of Data from the Randomized Trial to Prevent Vascular Events in Human Immunodeficiency Virus (REPRIEVE).
- Authors
Kileel, Emma M; Malvestutto, Carlos D; Lo, Janet; Fitch, Kathleen V; Fichtenbaum, Carl J; Aberg, Judith A; Zanni, Markella V; Martinez, Esteban; Okeke, Nwora Lance; Kumar, Princy; Joao, Esau; Bares, Sara H; Berrner, Daniel; Smieja, Marek; Roa, Jhoanna C; McCallum, Sara; Douglas, Pamela S; Ribaudo, Heather J; Grinspoon, Steven K
- Abstract
Over 2-years of follow-up, integrase strand transfer inhibitor (INSTI)-use was associated with weight gain among those on an INSTI <2 years at entry (+0.27 kg/m2/year; 95% confidence interval [CI],.22 to.33 vs +0.17 kg/m2/year; 95% CI,.12 to.23; P =.01), but not those on an entry INSTI >2 years.
- Subjects
HIV infections; DISEASE clusters; HIV integrase inhibitors; CONFIDENCE intervals; ANTIRETROVIRAL agents; TREATMENT duration; WEIGHT gain; TREATMENT effectiveness; RESEARCH funding; DESCRIPTIVE statistics; BODY mass index; LONGITUDINAL method
- Publication
Clinical Infectious Diseases, 2023, Vol 76, Issue 11, p2010
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciad107