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- Title
Using Whole-genome Sequencing to Determine the Timing of Secondary Tuberculosis in British Columbia, Canada.
- Authors
Romanowski, Kamila; Sobkowiak, Benjamin; Guthrie, Jennifer L; Cook, Victoria J; Gardy, Jennifer L; Johnston, James C
- Abstract
Combined with epidemiological data, whole-genome sequencing (WGS) can help better resolve individual tuberculosis (TB) transmission events to a degree not possible with traditional genotyping. We combine WGS data with patient-level data to calculate the timing of secondary TB among contacts of people diagnosed with active TB in British Columbia, Canada.
- Subjects
BRITISH Columbia; TUBERCULOSIS transmission; TUBERCULOSIS diagnosis; TUBERCULOSIS risk factors; SEQUENCE analysis; TIME; MEDICAL screening; GENOMES; INFECTIOUS disease transmission; GENOTYPES; CENTERS for Disease Control &; Prevention (U.S.)
- Publication
Clinical Infectious Diseases, 2021, Vol 73, Issue 3, p535
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciaa1224