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- Title
Risk factors for early postoperative cognitive dysfunction after non-coronary bypass surgery in Chinese population.
- Authors
Xu, Tao; Bo, Lulong; Wang, Jiafeng; Zhao, Zhenzhen; Xu, Zhiyun; Deng, Xiaoming; Zhu, Wenzhong
- Abstract
<bold>Background: </bold>The present study was performed to investigate the incidence of early postoperative cognitive dysfunction (POCD) after non-coronary bypass surgery and the potential risk factors in Chinese population.<bold>Methods: </bold>We performed a prospective study in a teaching tertiary hospital from May 2012 to August 2012. One hundred and seventy-six adult patients undergoing non-coronary bypass surgery were recruited. Mini-Mental State Examination (MMSE) score was evaluated before and 3 to 5 days after surgery. Patients with a MMSE score reduction of 2 was diagnosed with POCD.<bold>Results: </bold>The general incidence of POCD was 33.0%, with no significant difference between the types of surgeries. In the univariate analysis, POCD associated factors included age, duration of surgery, anesthesia, cardiopulmonary bypass (CPB), cross-clamp and rewarming, and sevoflurane concentration. However, only age, cross-clamp duration and sevoflurane concentration were demonstrated to be independent risk factors for POCD.<bold>Conclusion: </bold>Incidence of early POCD after non-coronary bypass surgery was relatively high in Chinese population. Advanced age, longer aortic cross-clamp duration and lower sevoflurane concentration was associated with a higher incidence of POCD.
- Publication
Journal of Cardiothoracic Surgery, 2013, Vol 8, Issue 1, p204
- ISSN
1749-8090
- Publication type
journal article
- DOI
10.1186/1749-8090-8-204