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- Title
Dynamic Aerobic Exercise Induces Baroreflex Improvement in Diabetic Rats.
- Authors
Jorge, Luciana; Da Pureza, Demilto Y.; Dias, Danielle da Silva; Conti, Filipe Fernandes; Irigoyen, Maria-Cláudia; De Angelis, Kátia
- Abstract
The objective of the present study was to investigate the effects of an acute aerobic exercise on arterial pressure (AP), heart rate (HR), and baroreflex sensitivity (BRS) in STZ-induced diabetic rats. Male Wistar rats were divided into control (n = 8) and diabetic (n = 8) groups. AP, HR, and BRS, which were measured by tachycardic and bradycardic (BR) responses to AP changes, were evaluated at rest (R) and postexercise session (PE) on a treadmill. At rest, STZ diabetes induced AP and HR reductions, associated with BR impairment. Attenuation in resting diabetes-induced AP (R: 103 ± 2 versus PE: 111 ± 3mmHg) and HR (R: 290±7 versus PE: 328±10 bpm) reductions and BR dysfunction (R:-0.70±0.06 versus PE:-1.21±0.09 bpm/mmHg) was observed in the postexercise period. In conclusion, the hemodynamic and arterial baro-mediated control of circulation improvement in the postexercise period reinforces the role of exercise in the management of cardiovascular risk in diabetes.
- Subjects
AEROBIC exercises; HEART beat; BAROREFLEXES; DIABETES; PEOPLE with diabetes; LABORATORY rats
- Publication
Experimental Diabetes Research, 2012, p1
- ISSN
1687-5214
- Publication type
Article
- DOI
10.1155/2012/108680