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- Title
Sterile Water Versus Chlorhexidine as Cleaning Agent for Clean Intermittent Catheterization in Children: A Randomized Controlled Trial.
- Authors
Zakaria, Nordin; Nasir, Ariffin; Van Rostenberghe, Hans; Ilias, Mohamad Ikram
- Abstract
Introduction: To compare the rate of urinary tract infection (UTI) between those who are using sterile water versus chlorhexidine 0.5% in aqueous solution as cleansing agent in CIC to children. Methods: This was a prospective, randomized controlled trial study conducted at Hospital Universiti Sains Malaysia (Hospital USM). Children aged 1 to 17 years old who were attending Pediatric Nephrology Clinic for neurogenic bladder on regular CIC were recruited into the study. They were randomized using computer generated block randomization method into sterile water (intervention) group or chlorhexidine (control) group. Urine samples were collected at day 14 of the study period and any clinical features suggestive of urinary tract infection (UTI) were documented and evaluated. Pearson Chi-square and Fischer Exact test were used to analyze the data. Results: A total of 46 patients were enrolled and randomized into intervention group (n=23) and control group (n=23). None of the patients from both groups developed symptomatic UTI. Seven patients from intervention group and eight patients from control group had asymptomatic bacteriuria (ABU) on day 14 of the study period (p value 0.67). Conclusion: There were no statistical differences in the rate of UTI and ABU between the groups using sterile water and chlorhexidine 0.5% in aqueous solution as cleansing agent during CIC procedure.
- Subjects
CHI-squared test; CHLORHEXIDINE; STATISTICAL correlation; FISHER exact test; NEUROGENIC bladder; STATISTICAL sampling; HEALTH self-care; STERILIZATION (Disinfection); WATER; RANDOMIZED controlled trials; BACTERIURIA; URINARY catheters; INTERMITTENT urinary catheterization; DESCRIPTIVE statistics; CATHETER-associated urinary tract infections
- Publication
International Medical Journal, 2020, Vol 27, Issue 6, p666
- ISSN
1341-2051
- Publication type
Article