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- Title
Parallel Input Channels to Mouse Primary Visual Cortex.
- Authors
Gao, Enquan; DeAngelis, Gregory C.; Burkhalter, Andreas
- Abstract
It is generally accepted that in mammals visual information is sent to the brain along functionally specialized parallel pathways, but whether the mouse visual system uses similar processing strategies is not known. It is important to resolve this issue because the mouse brain provides a tractable system for developing a cellular and molecular understanding of disorders affecting spatiotemporal visual processing. We have used single-unit recordings in mouse primary visual cortex to study whether individual neurons are more sensitive to one set of sensory cues than another. Our quantitative analyses show that neurons with short response latencies have low spatial acuity and high sensitivity to contrast, temporal frequency, and speed, whereas neurons with long latencies have high spatial acuity, low sensitivities to contrast, temporal frequency, and speed. These correlations suggest that neurons in mouse V1 receive inputs from a weighted combination of parallel afferent pathways with distinct spatiotemporal sensitivities.
- Subjects
VISUAL cortex; SPATIO-temporal variation; VISUAL perception; LEARNING disabilities; VISION disorders; QUANTITATIVE research
- Publication
Journal of Neuroscience, 2010, Vol 30, Issue 17, p5912
- ISSN
0270-6474
- Publication type
Article
- DOI
10.1523/JNEUROSCI.6456-09.2010