We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Multishot echo-planar imaging with gadopentetate dimeglumine. Preliminary study of efficacy for detection of hypovascular metastatic liver tumors.
- Authors
Murakami, T.; Kim, T.; Hori, M.; Takamura, M.; Tsuda, K.; Takahashi, S.; Narumi, Y.; Nakamura, H.
- Abstract
<bold>Objective: </bold>To evaluate the usefulness of sequential T2-weighted spin-echo type multishot echo-planar (T2-EP) imaging with gadopentetate dimeglumine for the detection of hypovascular metastatic liver tumors.<bold>Material and Methods: </bold>Fifteen consecutive patients with 56 proven hypovascular metastatic liver tumors were included in the study. Three observers blindly and independently read the whole-liver images obtained with T2-weighted spin-echo, T2-weighted single-shot fast spin-echo, T1-weighted fast multiplanar spoiled GRASS and T2-EP images obtained before and 25, 60, 90 and 120 s after injection of 0.2 mmol/kg b.w. of gadopentetate dimeglumine. The diagnostic accuracy was estimated by calculating the area under the observer-specific binomial receiver operating characteristics curves (Az).<bold>Results: </bold>T2-EP images obtained 60 s after contrast injection showed significantly higher contrast-to-noise (C/N) ratios than the other imaging techniques. A combination of all phases of the T2-EP images produced the highest sensitivity and specificity. In terms of the Az value, the diagnostic accuracy for tumor detection achieved with a combination of all phases of the T2-EP images was significantly higher than that with T1-SPGR and T2-SSFSE images (p<0.01). The Az values of the T2-EP images (Az=0.975) were higher than those of T2-CSE images (Az=0.948), but the difference was not significant.<bold>Conclusion: </bold>Our preliminary study revealed that sequential imaging with enhanced T2-EP images was useful for the detection of hypovascular metastatic liver tumors because of its superior C/N ratio and sensitivity.
- Subjects
LIVER tumors; DIAGNOSTIC imaging; METASTASIS; DIAGNOSIS; DIAGNOSTIC errors; DIGITAL image processing; INTRAVENOUS injections; MAGNETIC resonance imaging; PHARMACOKINETICS; TIME; RESEARCH bias; CONTRAST media; BLIND experiment; RECEIVER operating characteristic curves; MEDICAL artifacts
- Publication
Acta Radiologica, 2000, Vol 41, Issue 3, p263
- ISSN
0284-1851
- Publication type
journal article
- DOI
10.1080/028418500127345217