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The Immune System in Obesity: Developing Paradigms Amidst Inconvenient Truths.
Published in:
2017
By:
- Agrawal, Madhur;
- Kern, Philip;
- Nikolajczyk, Barbara;
- Kern, Philip A;
- Nikolajczyk, Barbara S
Publication type:
journal article
Severe Hypercalcemia From Inhalation Pneumonitis via Activation of 1,25 Dihydroxyvitamin D.
Published in:
Journal of the Endocrine Society, 2022, v. 6, n. 6, p. 1, doi. 10.1210/jendso/bvac066
By:
- Rosenstein, Kyle;
- Kern, Philip A
Publication type:
Article
Adrenal Vein Cortisol to Metanephrine Ratio for Localizing ACTH-Independent Cortisol-Producing Adenoma: A Case Report.
Published in:
2021
By:
- Raj, Rishi;
- Kern, Philip A;
- Ghanta, Neelima;
- Uy, Edilfavia M;
- Asadipooya, Kamyar
Publication type:
Case Study
Effect of Rifaximin Treatment on Endotoxemia and Insulin Sensitivity in Humans.
Published in:
Journal of the Endocrine Society, 2019, v. 3, n. 9, p. 1641, doi. 10.1210/js.2019-00148
By:
- Finlin, Brian S;
- Zhu, Beibei;
- Boyechko, Tania;
- Westgate, Philip M;
- Chia, Chee W;
- Egan, Josephine M;
- Kern, Philip A
Publication type:
Article
Senolytic treatment rescues blunted muscle hypertrophy in old mice.
Published in:
GeroScience, 2022, v. 44, n. 4, p. 1925, doi. 10.1007/s11357-022-00542-2
By:
- Dungan, Cory M.;
- Figueiredo, Vandre C.;
- Wen, Yuan;
- VonLehmden, Georgia L.;
- Zdunek, Christopher J.;
- Thomas, Nicholas T.;
- Mobley, C. Brooks;
- Murach, Kevin A.;
- Brightwell, Camille R.;
- Long, Douglas E.;
- Fry, Christopher S.;
- Kern, Philip A.;
- McCarthy, John J.;
- Peterson, Charlotte A.
Publication type:
Article
Associations of muscle lipid content with physical function and resistance training outcomes in older adults: altered responses with metformin.
Published in:
GeroScience, 2021, v. 43, n. 2, p. 629, doi. 10.1007/s11357-020-00315-9
By:
- Long, Douglas E.;
- Peck, Bailey D.;
- Tuggle, Steven C.;
- Villasante Tezanos, Alejandro G.;
- Windham, Samuel T.;
- Bamman, Marcas M.;
- Kern, Philip A.;
- Peterson, Charlotte A.;
- Walton, Rosicka G.
Publication type:
Article
Exploring the role of sex in the association of late chronotype on cardiorespiratory fitness.
Published in:
Physiological Reports, 2024, v. 12, n. 3, p. 1, doi. 10.14814/phy2.15924
By:
- Thomas, J. Matthew;
- Kern, Philip A.;
- Bush, Heather M.;
- Robbins, Sarah J.;
- Black, W. Scott;
- Pendergast, Julie S.;
- Clasey, Jody L.
Publication type:
Article
Cycle training modulates satellite cell and transcriptional responses to a bout of resistance exercise.
Published in:
Physiological Reports, 2016, v. 4, n. 18, p. n/a, doi. 10.14814/phy2.12973
By:
- Murach, Kevin A.;
- Walton, R. Grace;
- Fry, Christopher S.;
- Michaelis, Sami L.;
- Groshong, Jason S.;
- Finlin, Brian S.;
- Kern, Philip A.;
- Peterson, Charlotte A.
Publication type:
Article
Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue.
Published in:
Physiological Reports, 2015, v. 3, n. 6, p. n/a, doi. 10.14814/phy2.12415
By:
- Walton, R. Grace;
- Finlin, Brian S.;
- Mula, Jyothi;
- Long, Douglas E.;
- Zhu, Beibei;
- Fry, Christopher S.;
- Westgate, Philip M.;
- Lee, Jonah D.;
- Bennett, Tamara;
- Kern, Philip A.;
- Peterson, Charlotte A.
Publication type:
Article
Fasting and Glucose Metabolism Differentially Impact Peripheral Inflammation in Human Type 2 Diabetes.
Published in:
Nutrients, 2024, v. 16, n. 10, p. 1404, doi. 10.3390/nu16101404
By:
- Kalantar, Gabriella H.;
- Saraswat, Shubh;
- SantaCruz-Calvo, Sara;
- Gholamrezaeinejad, Fatemeh;
- Javidan, Aida;
- Agrawal, Madhur;
- Liu, Rui;
- Kern, Philip A.;
- Zhang, Xiaohua Douglas;
- Nikolajczyk, Barbara S.
Publication type:
Article
Inclusion of adrenal crisis in the differential diagnosis of distributive shock.
Published in:
American Journal of Health-System Pharmacy, 2020, v. 77, n. 6, p. 415, doi. 10.1093/ajhp/zxz324
By:
- Tompkins, Madeline G;
- Bissell, Brittany D;
- Sowders, Virginia;
- Kern, Philip A
Publication type:
Article
T cells dominate peripheral inflammation in a cross-sectional analysis of obesity-associated diabetes.
Published in:
2022
By:
- Pugh, Gabriella H.;
- Fouladvand, Sajjad;
- SantaCruz‐Calvo, Sara;
- Agrawal, Madhur;
- Zhang, Xiaohua Douglas;
- Chen, Jin;
- Kern, Philip A.;
- Nikolajczyk, Barbara S.;
- SantaCruz-Calvo, Sara
Publication type:
journal article
Aldose reductase promotes diet-induced obesity via induction of senescence in subcutaneous adipose tissue.
Published in:
2022
By:
- Thiagarajan, Devi;
- Quadri, Nosirudeen;
- Jawahar, Shabnam;
- Zirpoli, Hylde;
- del Pozo, Carmen Hurtado;
- López‐Díez, Raquel;
- Hasan, Syed Nurul;
- Yepuri, Gautham;
- Gugger, Paul F.;
- Finlin, Brian S.;
- Kern, Philip A.;
- Gabbay, Kenneth;
- Schmidt, Ann Marie;
- Ramasamy, Ravichandran;
- López-Díez, Raquel
Publication type:
journal article
Saturated Fatty Acid Activates T Cell Inflammation Through a Nicotinamide Nucleotide Transhydrogenase (NNT)-Dependent Mechanism.
Published in:
Biomolecules (2218-273X), 2019, v. 9, n. 2, p. 79, doi. 10.3390/biom9020079
By:
- McCambridge, Grace;
- Agrawal, Madhur;
- Keady, Alanna;
- Kern, Philip A.;
- Hasturk, Hatice;
- Nikolajczyk, Barbara S.;
- Bharath, Leena P.
Publication type:
Article
Human Body Composition and Immunity: Visceral Adipose Tissue Produces IL-15 and Muscle Strength Inversely Correlates with NK Cell Function in Elderly Humans.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00440
By:
- Al-Attar, Ahmad;
- Presnell, Steven R.;
- Clasey, Jody L.;
- Long, Douglas E.;
- Walton, R. Grace;
- Sexton, Morgan;
- Starr, Marlene E.;
- Kern, Philip A.;
- Peterson, Charlotte A.;
- Lutz, Charles T.
Publication type:
Article
Social Network Analysis to Assess the Impact of the CTSA on Biomedical Research Grant Collaboration.
Published in:
CTS: Clinical & Translational Science, 2015, v. 8, n. 2, p. 150, doi. 10.1111/cts.12247
By:
- Nagarajan, Radhakrishnan;
- Peterson, Charlotte A.;
- Lowe, Jane S.;
- Wyatt, Stephen W.;
- Tracy, Timothy S.;
- Kern, Philip A.
Publication type:
Article
Inhibition of LPL by PKCα depletion in adipocytes involves PKA activation.
Published in:
FASEB Journal, 2007, v. 21, n. 5, p. A238
By:
- Unal, Resat;
- Pokrovskaya, Irina D.;
- Tripathi, Preeti;
- Kern, Philip A.;
- Ranganathan, Gouri
Publication type:
Article
Insulinlike growth factor action and production in adipocytes and endothelial cells from human adipose tissue.
Published in:
1989
By:
- Kern, Philip A.;
- Svoboda, Marjorie E.;
- Eckel, Robert H.;
- Van Wyk, Judson J.;
- Kern, P A;
- Svoboda, M E;
- Eckel, R H;
- Van Wyk, J J
Publication type:
journal article
Regulation of lipoprotein lipase by glucose in primary cultures of isolated human adipocytes. Relevance to hypertriglyceridemia of diabetes.
Published in:
1987
By:
- Kern, Philip A.;
- Mandic, Angela;
- Eckel, Robert H.;
- Kern, P A;
- Mandic, A;
- Eckel, R H
Publication type:
journal article
Obesity and Fatty Acids Promote Mitochondrial Translocation of STAT3 Through ROS-Dependent Mechanisms.
Published in:
Frontiers in Aging, 2022, p. 1, doi. 10.3389/fragi.2022.924003
By:
- Conway, Rachel;
- Rockhold, Jack Donato;
- SantaCruz-Calvo, Sara;
- Zukowski, Emelia;
- Pugh, Gabriella H.;
- Hasturk, Hatice;
- Kern, Philip A.;
- Nikolajczyk, Barbara S.;
- Bharath, Leena P.
Publication type:
Article
142 A Community Mini-Grant Program: Community Leaders and Academic Partners Work Together to Improve Health in Appalachian Kentucky.
Published in:
2022
By:
- Hall, Ashley G.;
- Kern, Philip A.;
- Mudd-Martin
Publication type:
Abstract
A tribute to James E. "Jim" Heubi, MD.
Published in:
Journal of Clinical & Translational Science, 2022, v. 6, n. 1, p. 1, doi. 10.1017/cts.2022.21
By:
- Kern, Philip A.
Publication type:
Article
KL2 scholars' perceptions of factors contributing to sustained translational science career success.
Published in:
Journal of Clinical & Translational Science, 2022, v. 6, n. 1, p. 1, doi. 10.1017/cts.2021.886
By:
- Smyth, Susan S.;
- Coller, Barry S.;
- Jackson, Rebecca D.;
- Kern, Philip A.;
- McIntosh, Scott;
- Meagher, Emma A.;
- Rubio, Doris M.;
- Sandberg, Kathryn;
- Tsevat, Joel;
- Umans, Jason G.;
- Attia, Jacqueline;
- Baker, Heather L.;
- Nagel, Joan D.;
- McMullen, Colleen A.;
- Rosemond, Erica
Publication type:
Article
Adipose Tissue Hypoxia, Inflammation, and Fibrosis in Obese Insulin-Sensitive and Obese Insulin-Resistant Subjects.
Published in:
2016
By:
- Lawler, Helen M;
- Underkofler, Chantal M;
- Kern, Philip A;
- Erickson, Christopher;
- Bredbeck, Brooke;
- Rasouli, Neda
Publication type:
journal article
Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance.
Published in:
2011
By:
- Spencer, Michael;
- Unal, Resat;
- Zhu, Beibei;
- Rasouli, Neda;
- McGehee, Robert E Jr;
- Peterson, Charlotte A;
- Kern, Philip A
Publication type:
journal article
Insulin resistance in African-American and Caucasian women: differences in lipotoxicity, adipokines, and gene expression in adipose tissue and muscle.
Published in:
2010
By:
- Smith, Latasha M;
- Yao-Borengasser, Aiwei;
- Starks, Tasha;
- Tripputi, Mark;
- Kern, Philip A;
- Rasouli, Neda
Publication type:
journal article
Matrix metalloproteinase-9 is increased in obese subjects and decreases in response to pioglitazone.
Published in:
2010
By:
- Unal, Resat;
- Yao-Borengasser, Aiwei;
- Varma, Vijayalakshmi;
- Rasouli, Neda;
- Labbate, Craig;
- Kern, Philip A;
- Ranganathan, Gouri
Publication type:
journal article
The impact of exercise training compared to caloric restriction on hepatic and peripheral insulin resistance in obesity.
Published in:
2009
By:
- Coker, Robert H;
- Williams, Rick H;
- Yeo, Sophie E;
- Kortebein, Patrick M;
- Bodenner, Don L;
- Kern, Philip A;
- Evans, William J
Publication type:
journal article
Adipocytokines and the metabolic complications of obesity.
Published in:
2008
By:
- Rasouli, Neda;
- Kern, Philip A
Publication type:
journal article
Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects.
Published in:
2008
By:
- Sharma, Neeraj K;
- Das, Swapan K;
- Mondal, Ashis K;
- Hackney, Oksana G;
- Chu, Winston S;
- Kern, Philip A;
- Rasouli, Neda;
- Spencer, Horace J;
- Yao-Borengasser, Aiwei;
- Elbein, Steven C
Publication type:
journal article
Stearoyl-coenzyme A desaturase 1 gene expression increases after pioglitazone treatment and is associated with peroxisomal proliferator-activated receptor-gamma responsiveness.
Published in:
2008
By:
- Yao-Borengasser, Aiwei;
- Rassouli, Negah;
- Varma, Vijayalakshmi;
- Bodles, Angela M;
- Rasouli, Neda;
- Unal, Resat;
- Phanavanh, Bounleut;
- Ranganathan, Gouri;
- McGehee, Robert E Jr;
- Kern, Philip A
Publication type:
journal article
Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone.
Published in:
2007
By:
- Yao-Borengasser, Aiwei;
- Varma, Vijayalakshmi;
- Bodles, Angela M;
- Rasouli, Neda;
- Phanavanh, Bounleut;
- Lee, Mi-Jeong;
- Starks, Tasha;
- Kern, Leslie M;
- Spencer, Horace J 3rd;
- Rashidi, Amir Adel;
- McGehee, Robert E Jr;
- Fried, Susan K;
- Kern, Philip A
Publication type:
journal article
Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation.
Published in:
2007
By:
- Varma, Vijayalakshmi;
- Yao-Borengasser, Aiwei;
- Rasouli, Neda;
- Bodles, Angela M.;
- Phanavanh, Bounleut;
- Mi-Jeong Lee;
- Starks, Tasha;
- Kern, Leslie M.;
- Spencer, Horace J. III;
- McGehee, Robert E.;
- Fried, Susan K.;
- Kern, Philip A.
Publication type:
journal article
Effect of Weight Loss on Muscle Fiber Type, Fiber Size, Capillarity, and Succinate Dehydrogenase Activity in Humans.
Published in:
Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 11, p. 4185, doi. 10.1210/jcem.84.11.6090
By:
- KERN, PHILIP A.;
- SIMSOLO, ROSA B.;
- FOURNIER, MARIO
Publication type:
Article
Metformin blunts muscle hypertrophy in response to progressive resistance exercise training in older adults: A randomized, double‐blind, placebo‐controlled, multicenter trial: The MASTERS trial.
Published in:
Aging Cell, 2019, v. 18, n. 6, p. N.PAG, doi. 10.1111/acel.13039
By:
- Walton, R. Grace;
- Dungan, Cory M.;
- Long, Douglas E.;
- Tuggle, S. Craig;
- Kosmac, Kate;
- Peck, Bailey D.;
- Bush, Heather M.;
- Villasante Tezanos, Alejandro G.;
- McGwin, Gerald;
- Windham, Samuel T.;
- Ovalle, Fernando;
- Bamman, Marcas M.;
- Kern, Philip A.;
- Peterson, Charlotte A.
Publication type:
Article
Adipose Tissue Mast Cells Promote Human Adipose Beiging in Response to Cold.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45136-9
By:
- Finlin, Brian S.;
- Confides, Amy L.;
- Zhu, Beibei;
- Boulanger, Mary C.;
- Memetimin, Hasiyet;
- Taylor, Kyle W.;
- Johnson, Zachary R.;
- Westgate, Philip M.;
- Dupont-Versteegden, Esther E.;
- Kern, Philip A.
Publication type:
Article
Human skeletal muscle macrophages increase following cycle training and are associated with adaptations that may facilitate growth.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37187-1
By:
- Walton, R. Grace;
- Kosmac, Kate;
- Mula, Jyothi;
- Fry, Christopher S.;
- Peck, Bailey D.;
- Groshong, Jason S.;
- Finlin, Brian S.;
- Zhu, Beibei;
- Kern, Philip A.;
- Peterson, Charlotte A.
Publication type:
Article
Ectopic fat accumulation and metabolic syndrome.
Published in:
Diabetes, Obesity & Metabolism, 2007, v. 9, n. 1, p. 1, doi. 10.1111/j.1463-1326.2006.00590.x
By:
- Rasouli, Neda;
- Molavi, Behzad;
- Elbein, Steven C.;
- Kern, Philip A.
Publication type:
Article
Minimal alteration in muscle lipid genes following stabilized weight loss.
Published in:
Applied Physiology, Nutrition & Metabolism, 2017, v. 42, n. 12, p. 1277, doi. 10.1139/apnm-2017-0098
By:
- Coker, Robert H.;
- Robinette, Leizleigh;
- Kern, Philip A.
Publication type:
Article
Visceral Fat and Adiponectin: Associations with Insulin Resistance Are Tissue-Specific in Women.
Published in:
Metabolic Syndrome & Related Disorders, 2009, v. 7, n. 1, p. 61, doi. 10.1089/met.2008.0035
By:
- Robert H. Coker;
- Rick H. Williams;
- Sophie E. Yeo;
- Patrick M. Kortebein;
- Don L. Bodenner;
- Philip A. Kern;
- William J. Evans
Publication type:
Article
Calcium Is Involved in Formation of High Molecular Weight Adiponectin.
Published in:
Metabolic Syndrome & Related Disorders, 2008, v. 6, n. 2, p. 103, doi. 10.1089/met.2007.0033
By:
- Anannya Banga;
- Angela M. Bodles;
- Neda Rasouli;
- Gouri Ranganathan;
- Philip A. Kern;
- Randall J. Owens
Publication type:
Article
Improved β-cell function leads to improved glucose tolerance in a transgenic mouse expressing lipoprotein lipase in adipocytes.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-26995-1
By:
- Memetimin, Hasiyet;
- Zhu, Beibei;
- Lee, Sangderk;
- Katz, Wendy S.;
- Kern, Philip A.;
- Finlin, Brian S.
Publication type:
Article
Potential Benefits of Combined Statin and Metformin Therapy on Resistance Training Response in Older Individuals.
Published in:
Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.872745
By:
- Long, Douglas E.;
- Kosmac, Kate;
- Dungan, Cory M.;
- Bamman, Marcas M.;
- Peterson, Charlotte A.;
- Kern, Philip A.
Publication type:
Article
Regulatory T Cells Control Effector T Cell Inflammation in Human Prediabetes.
Published in:
2022
By:
- Liu, Rui;
- Pugh, Gabriella H.;
- Tevonian, Erin;
- Thompson, Katherine;
- Lauffenburger, Douglas A.;
- Kern, Philip A.;
- Nikolajczyk, Barbara S.
Publication type:
journal article
2023-P: Effect of Combination Therapy with a ß3 Adrenergic Receptor and PPARγ Agonist on Adipose Beiging in Obese Humans.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2023-P
By:
- KERN, PHILIP A.;
- MEMETIMIN, HASIYET;
- ZHU, BEIBEI;
- CONFIDES, AMY L.;
- JOHNSON, ZACHARY;
- VEKARIA, HEMENDRA J.;
- WESTGATE, PHILIP;
- SULLIVAN, PATRICK G.;
- DUPONT-VERSTEEGDEN, ESTHER E.;
- FINLIN, BRIAN
Publication type:
Article
2082-P: Pharmacological Induction of Brown and Beige Adipose Tissue.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2082-P
By:
- FINLIN, BRIAN;
- MEMETIMIN, HASIYET;
- CONFIDES, AMY L.;
- ZHU, BEIBEI;
- JOHNSON, ZACHARY R.;
- DUPONT-VERSTEEGDEN, ESTHER E.;
- KERN, PHILIP A.
Publication type:
Article
Mast Cells Promote Seasonal White Adipose Beiging in Humans.
Published in:
Diabetes, 2017, v. 66, n. 5, p. 1237, doi. 10.2337/db16-1057
By:
- Finlin, Brian S.;
- Zhu, Beibei;
- Confides, Amy L.;
- Westgate, Philip M.;
- Harfmann, Brianna D.;
- Dupont-Versteegden, Esther E.;
- Kern, Philip A.
Publication type:
Article
Mast Cells Promote Seasonal White Adipose Beiging in Humans.
Published in:
2017
By:
- Finlin, Brian S;
- Zhu, Beibei;
- Confides, Amy L;
- Westgate, Philip M;
- Harfmann, Brianna D;
- Dupont-Versteegden, Esther E;
- Kern, Philip A
Publication type:
journal article
Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Is Associated with Hyperinsulinemia and Insulin Resistance.
Published in:
Toxicological Sciences, 2000, v. 56, n. 2, p. 431, doi. 10.1093/toxsci/56.2.431
By:
- Cranmer, Morris;
- Louie, Shirley;
- Kennedy, Richard H.;
- Kern, Philip A.;
- Fonseca, Vivian A.
Publication type:
Article
Fibre type-specific satellite cell response to aerobic training in sedentary adults.
Published in:
Journal of Physiology, 2014, v. 592, n. 12, p. 2625, doi. 10.1113/jphysiol.2014.271288
By:
- Fry, Christopher S.;
- Noehren, Brian;
- Mula, Jyothi;
- Ubele, Margo F.;
- Westgate, Philip M.;
- Kern, Philip A.;
- Peterson, Charlotte A.
Publication type:
Article

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