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- Title
Is the urinary iodine/creatinine ratio applicable to assess short term individual iodine status in Chinese adults? Comparison of iodine estimates from 24-h urine and timed-spot urine samples in different periods of the day.
- Authors
Liu, Zhuan; Lin, Yixuan; Wu, Jiani; Chen, Diqun; Wu, Xiaoyan; Lan, Ying; Chen, Zhihui
- Abstract
Background: Urinary iodine concentration (UIC) is routinely used to evaluate the population iodine status while the uniform method for the individual level assessment is uncertain. Objectives: To explore the 24-h urinary iodine excretion (UIE) in five different periods of the day and the corresponding prediction equations respect by the use of creatinine-corrected UIC. Methods: We collected 24-h, spot and fasting urine in five periods of the day to estimate 24-h UIE by the six different prediction equations. We compared the estimated creatinine-corrected UIC to the collected 24-h UIE and identified the most suitable equations in each period of the day. Results: Among the six different prediction equations, the equation of Kawasaki T was the best to estimate the 24-h UIE by fasting urine among Chinese adults. Among the five periods of time, the equation of Knudsen N was the best to estimate the 24-h UIE in the non-morning period. Conclusion: Urinary iodine status at the individual level could be estimated by different creatinine-based equations at different periods of the day.
- Subjects
IODINE analysis; FASTING; URINE collection &; preservation; IODINE; CREATININE; ADULTS
- Publication
Nutrition & Metabolism, 2022, Vol 19, Issue 1, p1
- ISSN
1743-7075
- Publication type
Article
- DOI
10.1186/s12986-022-00656-6