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- Title
A survey of perioperative management of sickle cell disease in North America.
- Authors
Firth, Paul G.; McMillan, Kristen N.; Haberkern, Charles M.; Yaster, Myron; Bender, Michael A.; Goodwin, Salvatore R.
- Abstract
Children with sickle cell disease frequently undergo surgical procedures that are associated with acute exacerbations of the disease. Current perioperative management practices are unclear. We aimed at describing the current management. We conducted an electronic survey of North American members of the Society for Pediatric Anesthesia, in which we asked about their perioperative management of sickle cell disease. The response rate to valid addresses was 25% ( n = 510/2006). In four scenarios, (a patient with mild disease undergoing a minor procedure; a patient with mild disease undergoing a more invasive procedure; a patient with severe disease undergoing a minor procedure; and a patient with severe disease undergoing a more invasive procedure) 80%, 38%, 27%, and 16% of respondents, respectively, would rely on oral fluids to hydrate patients during the preoperative fast, while 13%, 34%, 44%, and 59%, respectively, would use intravenous fluid. For the same four scenarios, 64%, 28%, 33%, and 10%, respectively, would not transfuse patients in an attempt to prevent sickle cell exacerbations, while 17%, 49%, 36%, and 51%, respectively, would transfuse to a hemoglobin concentration of 10 g·dl. The tendencies to administer preoperative intravenous fluid and to transfuse blood increased with disease severity and procedure invasiveness ( P < 0.001). Although 89% felt comfortable managing patients with sickle cell disease, 73% thought an advisory statement on optimal perioperative management was needed. There is a wide variation in the management of children with sickle cell disease. Clinicians differentiate management based on disease severity and procedure type.
- Subjects
NORTH America; SICKLE cell anemia in children; DISEASE exacerbation; PEDIATRIC surgery; INTRAVENOUS anesthesia
- Publication
Pediatric Anesthesia, 2011, Vol 21, Issue 1, p43
- ISSN
1155-5645
- Publication type
Article
- DOI
10.1111/j.1460-9592.2010.03415.x