We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Influence of endurance training-induced weight loss on the levels of ghrelin and obestatin of obese women with polycystic ovary syndrome.
- Authors
Zehsaz, Farzad; Farhangi, Negin; Gahremani, Mehri
- Abstract
Background: Polycystic ovary syndrome is an observed plurimetabolic syndrome associated with central obesity and insulin resistance. Aims: The purpose of the present study was to investigate the effects of 12-week training program on weight loss, serum ghrelin, acylated ghrelin, des-acylated ghrelin, and obestatin levels in obese sedentary women with polycystic ovary syndrome (PCOS). Methods: To this end, thirty sedentary obese women with PCOS (mean age 31.07 ± 2.49 years, height 162.23 ± 2.39 cm, weight: 87.23 ± 4.48 kg, BMI 33.12 ± 0.92) were recruited from a multidisciplinary PCOS specialty clinic in Tabriz city in 2017 and evaluated before and after a 12-week training program, including 45 min per session of aerobic training at an intensity of 60–75% of age-predicted maximum heart rate (300 kcal/day). Results: After the exercise program, body weight, waist circumference, and percentage body fat mass were decreased. Also, fasting glucose, insulin, and serum acylated ghrelin levels were significantly decreased (P < 0.05), but serum obestatin levels were significantly increased after training program (P < 0.05). Furthermore, serum ghrelin and des-acylated ghrelin concentrations were not significantly changed after the training program (P > 0.05). Conclusions: The moderate aerobic exercise training is associated with improvements in obestatin and health profiles of obese women with PCOS without associated structured energy restriction.
- Subjects
AEROBIC exercises; OBESITY; SEDENTARY women
- Publication
Sport Sciences for Health, 2020, Vol 16, Issue 4, p703
- ISSN
1824-7490
- Publication type
Article
- DOI
10.1007/s11332-020-00646-2