We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Enantioselective Enzymatic Modification of Chiral Block Copolymers.
- Authors
Yeniad, Bahar; Naik, Hemantkumar; Koning, Cor E.; Heise, Andreas
- Abstract
Block copolymers comprising blocks with pendant hydroxy groups of opposite chirality are synthesized by RAFT polymerization of (R)- and (S)-1-(4-vinylphenyl)ethanol (1R and 1S) as monomers. Initially, poly(styrene) macro-RAFT agents are chain-extended with both enantiomeric monomers to obtain poly(styrene- b-1R) and poly(styrene- b-1S) with controlled molecular weight and low polydispersities. Enantioselective esterification with vinyl acetate by Candida Antarctica Lipase B (CALB) is only possible on the 1R-containing block copolymer. This concept is extended to a series of chiral block copolymers poly(1R- b-1S) which, apart from their optical rotation, all behave like very similar homopolymers. By enzymatic enantioselective esterification on the 1R-block, block copolymer structures were obtained.
- Publication
Macromolecular Chemistry & Physics, 2013, Vol 214, Issue 5, p556
- ISSN
1022-1352
- Publication type
Article
- DOI
10.1002/macp.201200633