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- Title
Application of High-Resolution Terahertz Spectroscopy for Studying Biofilms Typical of ENT Pathologies.
- Authors
Vaks, V. L.; Aizenshtadt, A. A.; Anfertev, V. A.; Domracheva, E. G.; Chernyaeva, M. B.; Mokeeva, P. P.; Kryazhev, D. V.
- Abstract
A biofilm as the main type of existence of bacterial associations, which has its spatial and metabolic structure, is formed on the mucosa in a human body. The study of the main pathobionts and their abilities for biofilm formation at chronic adenotonsillitis, with the identification of tissue metabolites and a comparative analysis confirming the effect of the pathogen, is carried out using the methods of high-resolution terahertz gas spectroscopy. The biofilms formed by Staphylococcus aureus, Streptococcus pyogenes, Klebsiella pneumoniae, and Enterobacter coli are studied to reveal products of their thermal decomposition and identify the set which is characteristic of microorganisms. The sets of thermal-decomposition products of biofilms for different microorganisms demonstrate the composition difference, which can be used to create metabolic profiles of bacteria and the medical diagnostics methods.
- Subjects
TERAHERTZ spectroscopy; BIOFILMS; STREPTOCOCCUS pyogenes; KLEBSIELLA pneumoniae; STAPHYLOCOCCUS aureus; HUMAN body
- Publication
Radiophysics & Quantum Electronics, 2023, Vol 66, Issue 7/8, p610
- ISSN
0033-8443
- Publication type
Article
- DOI
10.1007/s11141-024-10320-z