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- Title
Determination of Enantioselectivity and Enantiomeric Excess by Mass Spectrometry in the Absence of Chiral Chromatographic Separation: An Overview.
- Authors
Piovesana, Susy; Samperi, Roberto; Laganà, Aldo; Bella, Marco
- Abstract
This review describes the principles and instrumentation for the screening of asymmetric reactions by mass spectrometry. These techniques witnessed a significant advancement in the last few years. Although some of them are still at the proof-of-concept development stage, several applications might be foreseen in the field of combinatorial, high-throughput parallel catalyst screening.
- Subjects
ANALYTICAL chemistry; ENANTIOMERS; ENANTIOSELECTIVE catalysis; ASYMMETRIC synthesis; MASS spectrometry
- Publication
Chemistry - A European Journal, 2013, Vol 19, Issue 35, p11478
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.201300233