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- Title
Phytosynthesis of Silver Nanoparticle (AgNPs) Using Aqueous Leaf Extract of Knoxia sumatrensis (Retz.) DC. and Their Multi-Potent Biological Activity: An Eco-Friendly Approach.
- Authors
Loganathan, Settu; Selvam, Kuppusamy; Shivakumar, Muthugounder Subaramanian; Senthil-Nathan, Sengottayan; Vasantha-Srinivasan, Prabhakaran; Gnana Prakash, Dhakshinamoorthy; Karthi, Sengodan; Al-Misned, Fahad; Mahboob, Shahid; Abdel-Megeed, Ahmed; Ghaith, Aml; Krutmuang, Patcharin
- Abstract
Green synthesis of silver nanoparticles (AgNPs) has gained greater interest among chemists and researchers in this current scenario. The present research investigates the larvicidal and anti-proliferation activity of AgNPs derived from Knoxia sumatrensis aqueous leaf extract (K. sumatrensis-ALE) as a potential capping and reducing candidate. The synthesized AgNPs were characterized through-UV-spectra absorption peak at 425 nm. The XRD and FT-IR studied displayed the crystalline nature and presence of functional groups in prepared samples. FE-SEM showed the hexagonal shape of NPs with the size of 7.73 to 32.84 nm. The synthesized AgNPs displayed superior antioxidant and anti-proliferative activity (IC50 53.29 µg/mL) of breast cancer cell line (MCF-7). Additionally, larvicidal activity against mosquito vector Culex quinquefasciatus larvae delivered (LC50-0.40, mg/L, and LC90-15.83) significant mortality rate post treatment with synthesized AgNPs. Overall, the present research illustrates that the synthesized AgNPs have high biological potential and present a perfect contender in the pharmacological and mosquitocidal arena.
- Subjects
NANOPARTICLES; CULEX quinquefasciatus; SILVER; MOSQUITO vectors; TENSE (Grammar); SILVER nanoparticles
- Publication
Molecules, 2022, Vol 27, Issue 22, p7854
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules27227854