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- Title
Chemoprotection of the ovary: a leading role or a complementary strategy in fertility preservation?
- Authors
Massarotti, Claudia; Ammar, Omar F; Liperis, George; Mincheva, Mina; Fraire-Zamora, Juan J; Sharma, Kashish; Rosario, Roseanne; Winship, Amy L; Lambertini, Matteo; Makieva, Sofia
- Abstract
The article discusses the concept of chemoprotection of the ovary during chemotherapy as a potential strategy for fertility preservation. It highlights the challenges and limitations of current approaches to fertility preservation, such as cryopreservation, and explores the potential benefits of chemoprotection as a complementary strategy. The study by Wu et al. is referenced, which investigates the use of CHEK1/2 inhibitors to protect the ovary during chemotherapy. The article emphasizes the need for further research and validation of chemoprotective agents, as well as the importance of integrating fertility preservation considerations into oncological trials and drug development.
- Subjects
FERTILITY preservation; OVARIES; HORMONE therapy; OVARIAN reserve; OVARIAN follicle
- Publication
Human Reproduction, 2024, Vol 39, Issue 6, p1357
- ISSN
0268-1161
- Publication type
Article
- DOI
10.1093/humrep/deae069