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- Title
Perhydrolase-nanotube paint composites with sporicidal and antiviral activity.
- Authors
Grover, Navdeep; Douaisi, Marc; Borkar, Indrakant; Lee, Lillian; Dinu, Cerasela; Kane, Ravi; Dordick, Jonathan
- Abstract
AcT (perhydrolase) containing paint composites were prepared leading to broad-spectrum decontamination. AcT was immobilized onto multi-walled carbon nanotubes (MWNTs) and then incorporated into latex-based paints to form catalytic coatings. These AcT-based paint composites showed a 6-log reduction in the viability of spores of Bacillus cereus and Bacillus anthracis (Sterne) within 60 min. The paint composites also showed >4-log reduction in the titer of influenza virus (X-31) within 10 min (initially challenged with 10 PFU/mL). AcT-based paint composites were also tested using various perhydrolase acyl donor substrates, including propylene glycol diacetate (PGD), glyceryl triacetate, and ethyl acetate, with PGD observed to be the best among the substrates tested for generation of peracetic acid and killing of bacillus spores. The operational stability of paint composites was also studied at different relative humidities and temperatures to simulate real-life operation.
- Subjects
MULTIWALLED carbon nanotubes; NANOCOMPOSITE materials; BACILLUS cereus; BACILLUS anthracis; INFLUENZA viruses; PAINT research
- Publication
Applied Microbiology & Biotechnology, 2013, Vol 97, Issue 19, p8813
- ISSN
0175-7598
- Publication type
Article
- DOI
10.1007/s00253-012-4573-3