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- Title
骨代谢生化指标实验推荐方案.
- Authors
张萌萌; 张岩; 吴涤; 张东伟; 张智海; 吴岩; 赵国阳; 葛继荣; 黄宏兴; 张秀珍; 毛未贤; 马倩倩; 高远; 张晓梅; 李英华; 邹军; 史晓林; 邓伟民; 王永福; 郑洪新
- Abstract
The biochemical indicators of bone metabolism include calcium and phosphorus metabolism regulation indicators, bone formation markers, bone resorption markers, hormones and cytokines. The bone formation markers and bone resorption markers are collectively called bone turnover markers. Enzyme-linked immunosorbent assay, chemiluminescence immunoassay, electrochemiluminescence immunoassay, radioimmunoassay, immunoradioassay, high performance liquid chromatography and other method are currently used in clinical practice to detect the level of biochemical indicators of bone metabolism in blood and urine to understand the metabolism of bone tissue condition. Biochemical indicators of bone metabolism are used to evaluate the bone metabolism status, diagnostic classification of osteoporosis, predict fracture risk, evaluate the therapeutic effect of osteoporosis, and differential diagnosis of metabolic bone disease. This article reviewed the Chinese and English literature in recent years, summarized the detection method and principles of bone metabolism biochemical indicators, and proposed a recommended plan for bone metabolism biochemical indicators. It is expected to play an active role in the promotion and research of biochemical indicators of bone metabolism.
- Publication
Chinese Journal of Osteoporosis, 2021, Vol 27, Issue 10, p1405
- ISSN
1006-7108
- Publication type
Article
- DOI
10.3969/j.issn.1006-7108.2021.10.001